Evidence map›Paper›PMID 37715277›Full record

ArticlePilot and feasibility studies2023

A rehabilitation intervention to improve recovery after an episode of delirium in adults over 65 years (RecoverED): study protocol for a multi-centre, single-arm feasibility study.

Louise Allan, Abby O'Connell, Shruti Raghuraman, Alison Bingham, Abigail Laverick, Kirstie Chandler, James Connors, Benjamin Jones, Jinpil Um, Sarah Morgan-Trimmer and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Louise AllanUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Abby O'ConnellUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Shruti RaghuramanUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Alison BinghamUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Abigail LaverickUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Kirstie ChandlerUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
James ConnorsUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Benjamin JonesUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Jinpil UmUniversity of Exeter Medical School, University of Exeter, Exeter, UK. j.um@exeter.ac.uk.ORCID http://orcid.org/0000-0002-6314-0508
Sarah Morgan-TrimmerUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Rowan HarwoodSchool of Health Sciences, University of Nottingham, Nottingham, UK.
Victoria A GoodwinDepartment of Ageing and Rehabilitation, University of Exeter, Exeter, UK.
Obioha C UkoumunneDepartment of Health and Community Sciences, Faculty of Health and Life Sciences, National Institute for Health and Care Research (NIHR) Applied Research Collaboration (ARC) South West Peninsula (PenARC), University of Exeter, Exeter, EX1 2LU, UK.
Annie HawtonHealth Economics Group, University of Exeter Medical School, Exeter, UK.
Rob AndersonExeter HS&DR Evidence Synthesis Centre, Institute of Health Research, University of Exeter Medical School, University of Exeter, Exeter, UK.
Thomas JacksonInstitute of Inflammation and Ageing, University of Birmingham Research Laboratories, Queen Elizabeth Hospital, Mindelsohn Way, Edgbaston, Birmingham, B15 2WD, UK.
Alasdair M J MacLullichScottish Hip Fracture Audit (SHFA), NHS National Services Scotland, Edinburgh, UK.
Sarah RichardsonAGE Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK.
Daniel DavisMRC Unit for Lifelong Health and Ageing at UCL, London, WC1E 7HB, UK.
Lesley CollierFaculty of Health and Well-Being, University of Winchester, Winchester, SO22 4NR, UK.
William David StrainDiabetes and Vascular Medicine Research Centre, Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, EX2 5AX, UK.
Rachael LitherlandInnovations in Dementia, Exeter, UK.
Jon GlasbySchool of Social Policy, University of Birmingham, Birmingham, UK.
Linda ClareUniversity of Exeter Medical School, University of Exeter, Exeter, UK.

Funding

NIHR Programme Grants for Applied Research NIHR202338
6 · The paper itself

Abstract

backgroundDelirium affects over 20% of all hospitalised older adults. Delirium is associated with a number of adverse outcomes following hospital admission including cognitive decline, anxiety and depression, increased mortality and care needs. Previous research has addressed prevention of delirium in hospitals and care homes, and there are guidelines on short-term treatment of delirium during admission. However, no studies have addressed the problem of longer-term recovery after delirium and it is currently unknown whether interventions to improve recovery after delirium are effective and cost-effective. The primary objective of this feasibility study is to test a new, theory-informed rehabilitation intervention (RecoverED) in older adults delivered following a hospital admission complicated by delirium to determine whether (a) the intervention is acceptable to individuals with delirium and (b) a definitive trial and parallel economic evaluation of the intervention are feasible.

methodsThe study is a multi-centre, single-arm feasibility study of a rehabilitation intervention with an embedded process evaluation. Sixty participants with delirium (aged > 65 years old) and carer pairs will be recruited from six NHS acute hospitals across the UK. All pairs will be offered the intervention, with follow-up assessments conducted at 3 months and 6 months post-discharge home. The intervention will be delivered in participants' own homes by therapists and rehabilitation support workers for up to 10 intervention sessions over 12 weeks. The intervention will be tailored to individual needs, and the chosen intervention plan and goals will be discussed and agreed with participants and carers. Quantitative data on reach, retention, fidelity and dose will be collected and summarised using descriptive statistics. The feasibility outcomes that will be used to determine whether the study meets the criteria for progression to a definitive randomised controlled trial (RCT) include recruitment, delivery of the intervention, retention, data collection and acceptability of outcome measures. Acceptability of the intervention will be assessed using in-depth, semi-structured qualitative interviews with participants and healthcare professionals. DISCUSSION: Findings will inform the design of a pragmatic multi-centre RCT of the effectiveness and cost-effectiveness of the RecoverED intervention for helping the longer-term recovery of people with delirium compared to usual care.

trial registrationThe feasibility study was registered: ISRCTN15676570.

Indexed as

DeliriumDementiaFeasibility studyInterventionProcess evaluationRehabilitation

Identifiers

PMID37715277
PMCPMC10503099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.