Evidence map›Paper›PMID 37715259›Full record

ArticleJournal of nanobiotechnology2023

Thermosensitive black phosphorus hydrogel loaded with silver sulfadiazine promotes skin wound healing.

Jie Zhou, Tianjiao Li, Meili Zhang, Bo Han, Tao Xia, Shuangshuang Ni, Zhiyong Liu, Zhenyang Chen, Xing Tian

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Pharmaceutics · 2026
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  11. Recent advances on thermosensitive hydrogels-mediated precision therapy.Asian journal of pharmaceutical sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jie ZhouKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi, 832002, China.
Tianjiao LiKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi, 832002, China.
Meili ZhangKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi, 832002, China.
Bo HanKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi, 832002, China.
Tao XiaSinopharm Xinjiang Pharmaceutical Co. LTD, Urumqi, 830032, China.
Shuangshuang NiSinopharm Xinjiang Pharmaceutical Co. LTD, Urumqi, 830032, China.
Zhiyong LiuCollege of Chemistry and Chemical Engineering, Shihezi University, Shihezi, 832003, China. lzyongclin@sina.com.
Zhenyang ChenSinopharm Xinjiang Pharmaceutical Co. LTD, Urumqi, 830032, China. 8809358@qq.com.
Xing TianKey Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi, 832002, China. tianxingdeyoujian@163.com.
Shihezi University · CNChina National Pharmaceutical Group Corporation (China) · CN

Funding

Guiding Plan of Xinjiang Production, Construction Corps 2022ZD007he National Natural Science Foundation of China 81960334Postdoctoral Program 336399the open project of the Key Laboratory of Xinjiang Herbal Medicine Resources Utilization Ministry of Education 201801
6 · The paper itself

Abstract

Wounds can lead to skin and soft tissue damage and their improper management may lead to the growth of pathogenic bacteria at the site of injury. Identifying better ways to promote wound healing is a major unmet need and biomedical materials with the ability to promote wound healing are urgently needed. Here, we report a thermosensitive black phosphorus hydrogel composed of black phosphorus nano-loaded drug silver sulfadiazine (SSD) and chitosan thermosensitive hydrogel for wound healing. The hydrogel has temperature-sensitive properties and enables the continuous release of SSD under near-infrared irradiation to achieve synergistic photothermal and antibacterial treatment. Additionally, it exerts antibacterial effects on Staphylococcus aureus. In a rat skin injury model, it promotes collagen deposition, boosts neovascularization, and suppresses inflammatory markers. In summary, the excellent thermosensitivity, biocompatibility, and wound-healing-promoting qualities of the reported thermosensitive hydrogel make it suitable as an ideal wound dressing in the clinic.

Indexed as

HydrogelsSilver SulfadiazineAnimalsAnti-Bacterial AgentsPhosphorusRatsWound HealingAnti-Bacterial AgentsHydrogelsPhosphorusSilver SulfadiazineAntibacterialBlack phosphorus nanosheetNear-infrared lightTemperature sensitive hydrogelWound healing

Identifiers

PMID37715259
PMCPMC10503145
OpenAlexW4386784431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.