ArticleBMC psychiatry2023
Nonlinear relationship between sleep midpoint and depression symptoms: a cross-sectional study of US adults.
Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Article
- Sleep Health Dimensions From Wearables and Transdiagnostic Mental Health in Young Adolescents.JAMA pediatrics · 2026Article
- Nonlinear relationship between sleep midpoint and osteoarthritis: a cross-sectional study in US adults.Clinical rheumatology · 2026Article
- Observational
- Mediation role of telomere length in the relationship between physical activity and PhenoAge: A population-based study.Journal of exercise science and fitness · 2025Article
- U-shaped association between average daily sleep duration and depression among individuals with hypertension: a cross-sectional study based on NHANES 2017-2020.BMC psychiatry · 2025Article
- Association between dietary flavonoid intake and anxiety: data from NHANES 2017-2018.BMC public health · 2025Article
- Joint association of sleep onset time and sleep duration with depression in patients with chronic kidney disease: Insights from the NHANES 2015-2020.Preventive medicine reports · 2025Article
- Curvilinear relationship between life's crucial 9 and metabolic syndrome in U.S. adults: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Association Between Serum Uric Acid Levels and Skin Cancer: Results from NHANES Data and Mendelian Randomization Analysis.Clinical, cosmetic and investigational dermatology · 2025Article
- Association Between Daytime Sleepiness and Quality of Life in Chinese Adolescents: A Moderated Mediation of Cognitive Dysfunction and Depressive Symptoms.Neuropsychiatric disease and treatment · 2025Article
- Association between volatile organic compounds exposure and infertility risk among American women aged 18-45 years from NHANES 2013-2020.Scientific reports · 2024Article
- Association between physical activity patterns and symptoms of obstructive sleep apnea: a cross-sectional analysis of NHANES data.BMC pulmonary medicine · 2024Article
- Nonlinear and symptom specific associations between chronotype and depression.Scientific reports · 2024Article
- Sleep-wake changes and incident depressive symptoms in midlife women.Scientific reports · 2024Article
- Exploring the potential relationship between short sleep risks and cognitive function from the perspective of inflammatory biomarkers and cellular pathways: Insights from population-based and mice studies.CNS neuroscience & therapeutics · 2024Article
- Inverted U-shaped relationship between sleep duration and phenotypic age in US adults: a population-based study.Scientific reports · 2024Article
- The role of education attainment on 24-hour movement behavior in emerging adults: evidence from a population-based study.Frontiers in public health · 2024Article
- The Association of Sleep Duration and Sleep Quality With Depression and Anxiety Among Chinese Commercial Pilots.Depression and anxiety · 2024Article
- Opposing brain signatures of sleep in task-based and resting-state conditions.Nature communications · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the close relationship between sleep-wake cycles and depression symptoms, the relationship between sleep midpoint and depression symptoms in adults remains understudied.
methodsIn this cross-sectional study, 18280 adults aged ≥ 18 years from the National Health and Nutrition Examination Survey (NHANES) 2015-2020 were analyzed. Covariates included age, sex, race/ethnicity, education level, marital status, family income, body mass index, smoking status, drinking status, physical activity, comorbid condition, sleep duration, and sleep disturbance were adjusted in multivariate regression models.
resultsWeighted restricted cubic spline based on the complex sampling design of NHANES showed that in participants with a sleep midpoint from 2:18 AM to 6:30 AM, the prevalence of depression symptoms increased by 0.2 times (adjusted odds ratio [OR] = 1.20, 95% confidence interval [CI]: 1.08-1.33) per 1-h increment in sleep midpoint compared to the reference point of 2:18 AM. For participants with a sleep midpoint after 6:30 AM and before 2:18 AM the next day, the relationship between sleep midpoint and depression symptoms was not significant after adjusting for all covariates (adjusted OR = 1.01, 95% CI: 0.99-1.03).
conclusionsThe findings indicate a significant nonlinear association between sleep midpoint and depression symptoms in a nationally representative sample of adults.
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