Evidence map›Paper›PMID 37714951›Full record

ArticleScientific reports2023

Visible light-driven photocatalysts, quantum chemical calculations, ADMET-SAR parameters, and DNA binding studies of nickel complex of sulfadiazine.

Sachin B Pandya, Bhavesh N Socha, Rahul P Dubey, Urmila H Patel, R H Patel, Bhupesh S Bhatt, Parth Thakor, Sanjay Bhakhar, Nikhil Vekariya, Jignesh Valand

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sachin B PandyaDepartment of Physics, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India. sachinpandya561@gmail.com.
Bhavesh N SochaDepartment of Physics, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India. bhaveshkumarsocha@gmail.com.
Rahul P DubeyDepartment of Physics, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India.
Urmila H PatelDepartment of Physics, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India.
R H PatelDepartment of Materials Science, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India.
Bhupesh S BhattDepartment of Chemistry, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India.
Parth ThakorBapubhai Desaibhai Patel Institute of Paramedical Sciences, Charotar University of Science and Technology, Changa, India.
Sanjay BhakharDepartment of Physics, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India.
Nikhil VekariyaDepartment of Materials Science, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India.
Jignesh ValandDepartment of Materials Science, Sardar Patel University, Vallabh Vidyanagar, Anand, 388120, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 3D-supramolecular nickel integrated Ni-SDZ complex was synthesized using sodium salt of sulfadiazine as the ligand and nickel(II) acetate as the metal salt using a condensation process and slow evaporation approach to growing the single crystal. The metal complex was characterized for its composition, functional groups, surface morphology as well as complex 3D structure, by resorting to various analytical techniques. The interacting surface and stability as well as reactivity of the complex were carried out using the DFT platform. From ADMET parameters, human Intestinal Absorbance data revealed that the compound has the potential to be well absorbed, and also Ni-SDZ complex cannot cross the blood-brain barrier (BBB). Additionally, the complex's DNA binding affinity and in-vivo and in-vitro cytotoxic studies were explored utilizing UV-Vis absorbance titration, viscosity measurements, and S. pombe cells and brine shrimp lethality tests. In visible light radiation, the Ni-SDZ complex displayed exceptional photo-degradation characteristics of approximately 70.19% within 70 min against methylene blue (MB).

Indexed as

NickelSulfadiazineDNAHumansLightMethylene BlueDNAMethylene BlueNickelSulfadiazine

Identifiers

PMID37714951
PMCPMC10504334

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