Evidence map›Paper›PMID 37714942›Full record

ArticleScientific reports2023

Replicating superspreader dynamics with compartmental models.

Michael T Meehan, Angus Hughes, Romain R Ragonnet, Adeshina I Adekunle, James M Trauer, Pavithra Jayasundara, Emma S McBryde, Alec S Henderson

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael T MeehanAustralian Institute of Tropical Health and Medicine, James Cook University, Townsville, 4811, Australia. michael.meehan1@jcu.edu.au.
Angus HughesSchool of Public Health and Preventive Medicine, Monash University, Melbourne, 3800, Australia.
Romain R RagonnetSchool of Public Health and Preventive Medicine, Monash University, Melbourne, 3800, Australia.
Adeshina I AdekunleDefence Science and Technology Group, Department of Defence, Melbourne, 3207, Australia.
James M TrauerSchool of Public Health and Preventive Medicine, Monash University, Melbourne, 3800, Australia.
Pavithra JayasundaraSchool of Public Health and Preventive Medicine, Monash University, Melbourne, 3800, Australia.
Emma S McBrydeAustralian Institute of Tropical Health and Medicine, James Cook University, Townsville, 4811, Australia.
Alec S HendersonAustralian Institute of Tropical Health and Medicine, James Cook University, Townsville, 4811, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious disease outbreaks often exhibit superspreader dynamics, where most infected people generate no, or few secondary cases, and only a small fraction of individuals are responsible for a large proportion of transmission. Although capturing this heterogeneity is critical for estimating outbreak risk and the effectiveness of group-specific interventions, it is typically neglected in compartmental models of infectious disease transmission-which constitute the most common transmission dynamic modeling framework. In this study we propose different classes of compartmental epidemic models that incorporate transmission heterogeneity, fit them to a number of real outbreak datasets, and benchmark their performance against the canonical superspreader model (i.e., the negative binomial branching process model). We find that properly constructed compartmental models can capably reproduce observed superspreader dynamics and we provide the pathogen-specific parameter settings required to do so. As a consequence, we also show that compartmental models parameterized according to a binary clinical classification have limited support.

Indexed as

EpidemicsEpidemiological ModelsBenchmarkingDisease OutbreaksHumansModels, Statistical

Identifiers

PMID37714942
PMCPMC10504364

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.