ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023
Dissociable Effects of Alzheimer's Disease-Related Cognitive Dysfunction and Aging on Functional Brain Network Segregation.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 44 citations in OpenAlex.
- Comparative efficacy of dual- vs. single-node tACS in amnestic mild cognitive impairment: behavioral and EEG evidence.Translational psychiatry · 2026Trial
- Mapping Neuroanatomical Heterogeneity of Brain Aging Within a Clinically Defined Aging Reference Cohort.Bioengineering (Basel, Switzerland) · 2026Article
- Hierarchical organization of tau topography across the Alzheimer's disease continuum integrates amyloid, connectome, and intrinsic molecular vulnerability.Communications biology · 2026Article
- Contributions of Gray Matter Microstructure to Differences in Fluid Cognition and Episodic Memory Across the Healthy Adult Lifespan.Human brain mapping · 2026Article
- Correspondence of large-scale functional brain network decline across aging mice and humans.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Individualized Mapping of Functional Brain Networks in Older Adulthood.bioRxiv : the preprint server for biology · 2026Article
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- Effects of aerobic exercise intervention on the association between brain functional connectivity and cognition among older adults.Aging brain · 2026Article
- High brain network system segregation is differentially linked with cognitive performance across the life span.Network neuroscience (Cambridge, Mass.) · 2026Article
- Brain network segregation is associated with drug use severity in individuals with opioid use disorder.Drug and alcohol dependence · 2025Article
- Neural flexibility is higher in Alzheimer's disease and predicts Alzheimer's disease transition.Journal of Alzheimer's disease : JAD · 2025Article
- Age and Alzheimer's disease affect functional connectivity along separate axes of functional brain organization.bioRxiv : the preprint server for biology · 2025Article
- Variation in brain aging: A review and perspective on the utility of individualized approaches to the study of functional networks in aging.Neurobiology of aging · 2025Review
- Bifocal tACS over the primary sensorimotor cortices increases interhemispheric inhibition and improves bimanual dexterity.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Segregation of three resting-state brain networks predicts reappraisal success across the lifespan.Social cognitive and affective neuroscience · 2025Article
- High-resolution structural connectivity mediates age-related differences in functional connectivity and fluid cognition.Brain communications · 2025Article
- Research progress on brain network imaging biomarkers of subjective cognitive decline.Frontiers in neuroscience · 2025Review
- A whole-brain functional connectivity model of Alzheimer's disease pathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Reduced brain network segregation in alcohol use disorder: Associations with neurocognition.Addiction biology · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Alzheimer's disease (AD) is associated with changes in large-scale functional brain network organization. Individuals with AD exhibit less segregated resting-state brain networks compared with individuals without dementia. However, declines in brain network segregation are also evident as adult individuals grow older. Determining whether these observations reflect unique or overlapping alterations on the functional connectome of the brain is essential for understanding the impact of AD on network organization and incorporating measures of functional brain network organization toward AD characterization. Relationships between AD dementia severity and participant's age on resting-state brain system segregation were examined in 326 cognitively healthy and 275 cognitively impaired human individuals recruited through the Alzheimer's Disease Neuroimaging Initiative (ADNI) (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.