ArticleJournal of medical Internet research2023
The Potential of ChatGPT as a Self-Diagnostic Tool in Common Orthopedic Diseases: Exploratory Study.
Article in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07733752 (When AI Is the First Clinician), which is not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
When AI Is the First Clinician: Impact of Pre-Visit AI Use on Presentation, Diagnostic Expectations, and Shared Decision-Making in Spine Physical Therapy
Who cites it
70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Large Language Models for Chatbot Health Advice Studies: A Systematic Review.JAMA network open · 2025Pooled it
- Clinical applications of large language models in knee osteoarthritis: a systematic review.Frontiers in medicine · 2025Pooled it
- Examining the Role of Large Language Models in Orthopedics: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Performance of ChatGPT Across Different Versions in Medical Licensing Examinations Worldwide: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Diagnostic Accuracy of Multimodal Large Language Models (LLMs) for Detecting Tuberous Breast Deformity from Standardized Photographs: A Descriptive in Silico Study.Aesthetic plastic surgery · 2026Article
- Do ChatGPT and Gemini's Recommendations Align With Established Guidelines for Hand and Upper Extremity Surgery?Hand (New York, N.Y.) · 2026Article
- Factors Shaping Trust and Satisfaction With AI Medical Chatbots: A Mixed Methods Vignette Survey of Caregivers Seeking Guidance on Pediatric Infectious Diseases.Journal of medical Internet research · 2026Article
- Navigating Diabetes Management in the Digital Era: Scoping Review of Online Health Information-Seeking Behavior.Journal of medical Internet research · 2026Article
- DeepSeek vs ChatGPT vs Claude: benchmarking large language models for clinical diagnosis using a novel ICD-10-CM-based evaluation framework.BMC medical informatics and decision making · 2026Article
- The Use of Chat-GPT 5.2 by Patients Affected by Rotator Cuff Tears Leads to Inaccurate Diagnosis and Treatment Suggestions: A Study by SICSeG (Italian Society of Shoulder and Elbow Surgery).Journal of clinical medicine · 2026Article
- Benchmarking of large language models to determine candidacy for spine surgery and comparison with conventional machine learning.BMC musculoskeletal disorders · 2026Article
- Evaluation of GPT-5 in Periodontitis Staging and Grading: Retrospective Observational Study.JMIR formative research · 2026Observational
- Large language model detects previously undiagnosed heart failure with preserved ejection fraction in patients with metabolic-associated fatty liver disease: A multicenter cohort study.PLOS digital health · 2026Article
- Article
- Patient Perceptions of Artificial Intelligence-Generated Kidney Transplant Information: Comparing ChatGPT With the National Kidney Foundation.Kidney medicine · 2026Article
- Artificial intelligence and machine learning based predictive analytics in cervical myelopathy - a scoping review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Performance of ChatGPT-4o, Gemini 2.0 Pro, and DeepSeek-V3 in Patient-Facing Information on Chest Wall Deformities: A Comparative Evaluation of Accuracy, RELIABILITY, and Reproducibility.Diagnostics (Basel, Switzerland) · 2026Article
- An Exploratory Evaluation of GPT-5 in Periodontitis Staging and Grading Using Published Clinical Cases.Research square · 2026Article
- Evaluation of GPT-5.2 for melanoma detection across skin tones.Frontiers in medicine · 2026Article
- High patient and surgeon satisfaction with ChatGPT-generated responses to real patient questions regarding total knee arthroplasty.Journal of orthopaedic surgery and research · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArtificial intelligence (AI) has gained tremendous popularity recently, especially the use of natural language processing (NLP). ChatGPT is a state-of-the-art chatbot capable of creating natural conversations using NLP. The use of AI in medicine can have a tremendous impact on health care delivery. Although some studies have evaluated ChatGPT's accuracy in self-diagnosis, there is no research regarding its precision and the degree to which it recommends medical consultations.
objectiveThe aim of this study was to evaluate ChatGPT's ability to accurately and precisely self-diagnose common orthopedic diseases, as well as the degree of recommendation it provides for medical consultations.
methodsOver a 5-day course, each of the study authors submitted the same questions to ChatGPT. The conditions evaluated were carpal tunnel syndrome (CTS), cervical myelopathy (CM), lumbar spinal stenosis (LSS), knee osteoarthritis (KOA), and hip osteoarthritis (HOA). Answers were categorized as either correct, partially correct, incorrect, or a differential diagnosis. The percentage of correct answers and reproducibility were calculated. The reproducibility between days and raters were calculated using the Fleiss κ coefficient. Answers that recommended that the patient seek medical attention were recategorized according to the strength of the recommendation as defined by the study.
resultsThe ratios of correct answers were 25/25, 1/25, 24/25, 16/25, and 17/25 for CTS, CM, LSS, KOA, and HOA, respectively. The ratios of incorrect answers were 23/25 for CM and 0/25 for all other conditions. The reproducibility between days was 1.0, 0.15, 0.7, 0.6, and 0.6 for CTS, CM, LSS, KOA, and HOA, respectively. The reproducibility between raters was 1.0, 0.1, 0.64, -0.12, and 0.04 for CTS, CM, LSS, KOA, and HOA, respectively. Among the answers recommending medical attention, the phrases "essential," "recommended," "best," and "important" were used. Specifically, "essential" occurred in 4 out of 125, "recommended" in 12 out of 125, "best" in 6 out of 125, and "important" in 94 out of 125 answers. Additionally, 7 out of the 125 answers did not include a recommendation to seek medical attention.
conclusionsThe accuracy and reproducibility of ChatGPT to self-diagnose five common orthopedic conditions were inconsistent. The accuracy could potentially be improved by adding symptoms that could easily identify a specific location. Only a few answers were accompanied by a strong recommendation to seek medical attention according to our study standards. Although ChatGPT could serve as a potential first step in accessing care, we found variability in accurate self-diagnosis. Given the risk of harm with self-diagnosis without medical follow-up, it would be prudent for an NLP to include clear language alerting patients to seek expert medical opinions. We hope to shed further light on the use of AI in a future clinical study.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.