Evidence map›Paper›PMID 37713102›Full record

ArticleIndian journal of pediatrics2024

Normative Data on Dehydroepiandrosterone Sulphate (DHEAS) and its Attributes in Healthy Indian Children and Adolescents.

Bhanu Malhotra, K V Ravi Teja, Shariq R Masoodi, Liza Das, Soham Mukherjee, Ashu Rastogi, Arshiya Dutta, Shallu Singhmar, Naresh Sachdeva, Raman Kumar Marwaha and 1 more

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Article in Indian journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bhanu Malhotra *Department of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
K V Ravi TejaDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Shariq R MasoodiDepartment of Endocrinology, Sher-e-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, India.
Liza DasDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Soham MukherjeeDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Ashu RastogiDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Arshiya DuttaMBBS Student, ATAL University, Shimla, Himachal Pradesh, India.
Shallu SinghmarDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Naresh SachdevaDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Raman Kumar MarwahaSociety of Endocrine Health Care for Elderly, Adolescents and Children (SEHEAC), New Delhi, India.
Pinaki DuttaDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India. drpinakidutta12@gmail.com.ORCID 0000-0001-5415-1611

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dehydroepiandrosterone sulphate (DHEAS), the biochemical indicator of adrenarche and pubarche, is of paramount importance in the evaluation of puberty-related disorders. The reference range of DHEAS should be ethnicity, age, sex, pubarche and Tanner stage specific. Anthropometry, puberty assessment and hormonal parameters were estimated using electrochemiluminescence assay. Bone age was estimated using the BoneXpert software. Of 2191 healthy Indian children aged 5-18 y screened at Chandigarh, 1919 were included in the final analysis (994 boys). The median DHEAS levels at pubarche stage P2 were 82.10 (55.0-129.0) g/dl in girls and 132.50 (95.12-205.50) g/dl in boys. By ROC analysis, the level of DHEAS at pubarche was 63.7 g/dl (sensitivity 72.6%, specificity 64.4%) in girls and 82.2 g/dl (sensitivity 81.8%, specificity 68.8%) in boys. The median age at adrenarche was 9.5 y in both sexes. On multivariate regression analysis; bone age, body mass index (BMI), gonadal steroids, and insulin-like growth factor-1 (IGF-1) significantly correlated with serum DHEAS levels in either sex.

Indexed as

Dehydroepiandrosterone SulfateAdolescentAdrenarcheAge Determination by SkeletonBody Mass IndexChildChild, PreschoolFemaleHumansIndiaInsulin-Like Growth Factor IMalePubertyReference ValuesDehydroepiandrosterone SulfateInsulin-Like Growth Factor IAdrenarcheBMIBone ageBone age/Chronological ageDHEASPubarche

Identifiers

PMID37713102

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.