Evidence map›Paper›PMID 37713092›Full record

ArticleEuropean geriatric medicine2024

Clinical presentation and outcome of hemodialysis tunneled catheter-related bloodstream infection in older persons.

Alon Bnaya, Yuval Schwartz, Orit Wolfovitz Barchad, Jawad Atrash, Maskit Bar-Meir, Linda Shavit, Eli Ben-Chetrit

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Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Identification and Characterization of aInfection and drug resistance · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alon BnayaInstitute of Nephrology, Shaare Zedek Medical Center, Affiliated with the Hebrew University, Jerusalem, Israel.
Yuval SchwartzInfectious Diseases Unit, Shaare Zedek Medical Center, Affiliated with the Hebrew University, P.O Box 3235, 91031, Jerusalem, Israel.
Orit Wolfovitz BarchadInfectious Diseases Unit, Shaare Zedek Medical Center, Affiliated with the Hebrew University, P.O Box 3235, 91031, Jerusalem, Israel.
Jawad AtrashInstitute of Nephrology, Shaare Zedek Medical Center, Affiliated with the Hebrew University, Jerusalem, Israel.
Maskit Bar-MeirPediatric Infectious Diseases, Shaare Zedek Medical Center, Affiliated with the Hebrew University, Jerusalem, Israel.
Linda ShavitInstitute of Nephrology, Shaare Zedek Medical Center, Affiliated with the Hebrew University, Jerusalem, Israel.
Eli Ben-ChetritInfectious Diseases Unit, Shaare Zedek Medical Center, Affiliated with the Hebrew University, P.O Box 3235, 91031, Jerusalem, Israel. elibc@szmc.org.il.ORCID http://orcid.org/0000-0001-5743-1387
Shaare Zedek Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of a tunneled catheter as the primary vascular access among old hemodialysis patients is frequent. Catheter-related bloodstream infection (CRBSI) is a common complication, associated with increased mortality. Data regarding the clinical presentation and outcomes of CRBSI among old hemodialysis patients is limited.

methodsAll chronic hemodialysis patients hospitalized between 2010 and 2022 with CRBSI were included. Patients were classified into two groups: old adults (≥ 75) and younger patients. Clinical, microbiological, and outcome data were collected and analyzed.

resultsOne hundred and fifty-four patients with CRBSI were identified. Fifty-seven were aged ≥ 75 years. Mean age in the older and younger groups was 81.2 ± 5 and 59.7 ± 12.7, respectively. Male gender was predominant (64%). Charlson comorbidity score and Pitt bacteremia score were comparable among both groups. Norton score < 14 was more common among old persons (n = 24, 67% versus n = 21, 31%, p < 0.001), as well as nursing-home residence. Gram-negative pathogens and Staphylococcus aureus were common in both groups. The frequency of inappropriate empirical antimicrobial treatment was higher among older persons. Overall, in-hospital and 90-day mortality was high (age ≥ 75, 36.8%, age < 75, 24.7%, p = 0.14). Age was not significantly associated with mortality after adjustment for low Norton score, residence, and inappropriate antimicrobial therapy as well as resistance patterns of bloodstream isolates [OR = 1.2 (95% CI 0.4-3.3), p = 0.76].

conclusionsClinical characteristics and outcomes of CRBSI were comparable among old and young hemodialysis patients. However, the high mortality rate in this cohort suggests that the use of tunneled catheters as a permanent vascular access should be discouraged in both patient groups.

Indexed as

Anti-Infective AgentsBacteremiaCatheter-Related InfectionsCentral Venous CathetersAgedAged, 80 and overHumansMaleRenal DialysisAnti-Infective AgentsBloodstream infectionHemodialysisTunneled catheter

Identifiers

PMID37713092
OpenAlexW4386757825

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.