ArticleJournal of the American Chemical Society2023
Methyl Ketones as Alkyl Halide Surrogates: A Deacylative Halogenation Approach for Strategic Functional Group Conversions.
Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed.
- Biginelli dihydropyrimidines: a tunable class of alkyl radical precursors.Chemical science · 2026Article
- Cross-ketone deacylative coupling via oxidative SNature communications · 2026Article
- An IntegratedACS catalysis · 2026Article
- Deacylative Polyfluoroarylation via C-C Cleavage of Alkyl Ketones.Organic letters · 2025Article
- Redox-neutral photocatalytic hydrodealkenylation of aryl olefins.Nature communications · 2025Article
- Carbonyl-to-sulfur swap enabled by sequential double carbon-carbon bond activation.Science (New York, N.Y.) · 2025Article
- Deacylative Homolysis of Ketone C(spJournal of the American Chemical Society · 2025Article
- Halodealkenylation: Ozonolysis and Catalytic FeOrganic letters · 2024Article
- Shuttle HAT for mild alkene transfer hydrofunctionalization.Nature communications · 2024Article
- Deacylative arylation and alkynylation of unstrained ketones.Science advances · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Alkyl halides are versatile precursors to access diverse functional groups (FGs). Due to their lability, the development of surrogates for alkyl halides is strategically important for complex molecule synthesis. Given the stability and ease of derivatization inherent in common alkyl ketones, here we report a deacylative halogenation approach to convert various methyl ketones to the corresponding alkyl chlorides, bromides, and iodides. The reaction is driven by forming an aromatic byproduct, i.e., 1,2,4-triazole, in which
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.