Evidence map›Paper›PMID 37712328›Full record

ArticleOrthopaedic surgery2023

A Novel Semi-Cannulated Screw Enhanced Bone Cement Augmentation and Pullout Strength in Posterior Cervical Lateral Mass Screw Fixations: An In Vitro Biomechanical and Morphological Study.

Huang Canyang, Chen Weidong, Huang Zhiping, Wu Xiuhua, Zheng Minghui, Huang Haihong, Zhu Qingan, Qu Dongbin

Open access · goldAbstract read
In one paragraph

Article in Orthopaedic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Huang CanyangDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Chen WeidongDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Huang ZhipingDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wu XiuhuaDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zheng MinghuiDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Huang HaihongDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhu QinganDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qu DongbinDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-4070-7524
Nanfang Hospital · CNFujian Medical University · CN

Funding

National Natural Science Foundation of China NO. 81272022Young and middle-aged backbone training project in the health system of Fujian province 2021GGA070
6 · The paper itself

Abstract

objectiveTo develop a novel semi-cannulated lateral mass screw (SC-LMS) for cervical posterior fixations and compare the fixation stability and safety of SC-LMS with regular solid lateral mass screw (S-LMS) in bone cement augmentation and pullout strength using fresh cadaveric cervical vertebrae.

methodsThe conventional multiaxial screw for cervical lateral mass fixation was modified to a cannulated screw with two lateral holes, used for bone cement injection in situ. Eight fresh human cervical vertebrae (C3, C4, and C5) were collected and used. μCT scan was performed to evaluate the bone quality of the lateral masses, including bone mineral density (BMD), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp). SCLMS or S-LMS were randomly inserted into the paired cervical vertebrae and pulled out as a screw loosening model. These screws were reinserted in with bone cement augmentation, scanned by μCT to obtain the bone cement distribution along the screws, and pulled out to test the screw purchase strength.

resultsFmax values exhibited strong positive correlations with the local BMD (𝑟 = 0.8640, p < 0.0001) and Tb.Th (𝑟 = 0.6795, p = 0.0038), whereas a negative correlation with Tb.Sp (𝑟 = -0.5567, p = 0.0251). A significant difference was observed between the Fmax before and after PMMA injection on the SC-LMS side (p = 0.019). The SC-LMS exhibited lower risk of cement leakage than S-LMS after PMMA injection, and a positive correlation was observed between 𝐹max and the distribution volumes on the SC-LMS side.

conclusionThe novel SC-LMS provides more robust fixation stability and is safer than the S-LMS for PMMA augmentation, which may be related to the cement-screw-cement-bone complex formation.

Indexed as

Bone CementsPolymethyl MethacrylateBiomechanical PhenomenaBone DensityBone ScrewsCervical VertebraeHumansBone CementsPolymethyl MethacrylateLateral Mass ScrewPull-Out StrengthScrew LooseningSemi-Cannulated

Identifiers

PMID37712328
PMCPMC10622296
OpenAlexW4386758040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.