Evidence map›Paper›PMID 37712325›Full record

ArticleThe Clinical journal of pain2023

Risk Factors for Self-Harm Ideation Among Persons Treated With Opioids for Chronic Low Back Pain.

Robert N Jamison, Robert R Edwards, Roger Brown, Bruce P Barrett, Cindy A Burzinski, Robert P Lennon, Yoshio Nakamura, Tony Schiefelbein, Eric L Garland, Aleksandra E Zgierska

Open access · greenAbstract read
In one paragraph

Article in The Clinical journal of pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Robert N JamisonDepartments of Anesthesiology, Harvard Medical School, Brigham and Women's Hospital, Perioperative and Pain Medicine and Psychiatry, Chestnut Hill, MA.
Robert R EdwardsDepartments of Anesthesiology, Harvard Medical School, Brigham and Women's Hospital, Perioperative and Pain Medicine and Psychiatry, Chestnut Hill, MA.
Roger BrownDepartment of Family Medicine and Community Health, University of Wisconsin-Madison, School of Medicine and Public Health.
Bruce P BarrettDepartment of Family Medicine and Community Health, University of Wisconsin-Madison, School of Medicine and Public Health.
Cindy A BurzinskiDepartment of Family Medicine and Community Health, University of Wisconsin-Madison, School of Nursing, Madison, WI.
Robert P LennonDepartment of Family and Community Medicine, Pennsylvania State University College of Medicine, Hershey, PA.
Yoshio NakamuraDepartment of Anesthesiology, University of Utah School of Medicine, Division of Pain Medicine, Pain Research Center.
Tony SchiefelbeinDepartment of Family and Community Medicine, Pennsylvania State University College of Medicine, Hershey, PA.
Eric L GarlandUniversity of Utah, Center on Mindfulness and Integrative Health Intervention Development, College of Social Work, Salt Lake City, UT.
Aleksandra E ZgierskaDepartment of Family and Community Medicine, Pennsylvania State University College of Medicine, Hershey, PA.
University of Utah · USUniversity of Wisconsin–Madison · USBrigham and Women's Hospital · USChestnut Hill College · USPennsylvania State University · USWisconsin Division of Public Health · US

Funding

Patient-Centered Outcomes Research Institute OPD-1601-33860
6 · The paper itself

Abstract

objectivesChronic pain is a significant health concern that adversely affects all aspects of life, including emotional well-being. Opioids are prescribed for the management of refractory, severe chronic pain, although they have been associated with adverse effects, including addiction and overdose. The aim of this study was to examine factors that predict thoughts of self-harm among adults with chronic pain who are prescribed opioids. MATERIALS AND

methodsSeven hundred sixty-five (N=765) persons with opioid-treated chronic lower back pain completed the Current Opioid Misuse Measure (COMM) and other validated questionnaires as part of a larger study. Response to 1 question from the COMM ("How often have you seriously thought about hurting yourself?") was used to assess suicide risk on a 5-point scale (0=never; 4=very often).

resultsParticipants were categorized into 3 groups according to their responses to the self-harm question: never (N=628; 82.1%), seldom or sometimes (N=74; 9.7%), and often or very often (N=63; 8.2%). Multivariate adjusted odds ratio (aOR) analyses indicated that reports of alcohol or drug overuse within the past month (aOR=1.41,[95% CI 1.11-1.78]), posttraumatic stress (PTSD; aOR=1.24,[1.07 to 1.44]), pain catastrophizing (aOR=1.03,[1.01 to 1.05]), not loving oneself (aOR=0.99,[.98-1.00]) and poor perceived mental health (aOR=0.94,[.92 to 97]) were most associated with thoughts of self-harm. Importantly, the ideation frequency of self-harm was highest among individuals treated with higher daily doses of opioids. DISCUSSION: These results support the need for continued monitoring of adults treated with opioids for chronic pain, particularly among those on high-dose opioids who present with increased negative affect and concerns of substance misuse.

Indexed as

Chronic PainLow Back PainOpioid-Related DisordersSelf-Injurious BehaviorAdultAnalgesics, OpioidHumansRisk FactorsAnalgesics, Opioid

Identifiers

PMID37712325
PMCPMC10695275
OpenAlexW4386757691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.