Evidence map›Paper›PMID 37712050›Full record

ArticleNpj mental health research2023

miR-124-3p target genes identify globus pallidus role in suicide ideation recovery in borderline personality disorder.

Macarena S Aloi, Guillermo F Poblete, John Oldham, Michelle A Patriquin, David A Nielsen, Thomas R Kosten, Ramiro Salas

Abstract read
In one paragraph

Article in Npj mental health research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Epigenetic Mechanisms of Suicidal Behavior Formation: A Review.Medical journal of the Islamic Republic of Iran · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Macarena S AloiMenninger Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
Guillermo F PobleteThe Menninger Clinic, Baylor College of Medicine, Houston, TX, USA.
John OldhamMenninger Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
Michelle A PatriquinMenninger Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
David A NielsenMenninger Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
Thomas R KostenMenninger Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
Ramiro SalasMenninger Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-1105-566X

Funding

TRAINING PROGRAM IN COMPUTATIONAL BIOLOGY AND MEDICINET15LM007093 · NLM · RICE UNIVERSITY · PI Lydia E. Kavraki · 1992 to 2026
$20.8M
Multimodal Imaging of Reward Brain Centers in Tobacco Smoking VeteransI01CX000994 · VA · MICHAEL E DEBAKEY VA MEDICAL CENTER · PI SALAS, RAMIRO · 2014 to 2016
–
Brain connectivity and genetics as predictors of opioid abuse treatment outcomesI01CX001937 · VA · MICHAEL E DEBAKEY VA MEDICAL CENTER · PI SALAS, RAMIRO · 2021 to 2025
–
CSRD VA I01 CX000994CSRD VA I01 CX001937NLM NIH HHS T15 LM007093
6 · The paper itself

Abstract

Borderline personality disorder (BPD) is characterized by patterns of unstable affect, unstable interpersonal relationships, and chronic suicidal tendencies. Research on the genetics, epigenetics, and brain function of BPD is lacking. MicroRNA-124-3p (miR-124-3p) was recently identified in a Genome-Wide Association Study as likely associated with BPD. Here, we identified the anatomical brain expression of genes likely modulated by miR-124-3p and compared morphometry in those brain regions in BPD inpatients vs. controls matched for psychiatric comorbidities. We isolated lists of targets likely modulated by miR-124-3p from TargetScan (v 8.0) by their preferentially conserved targeting (Aggregate P

Identifiers

PMID37712050
PMCPMC10500603

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.