Evidence map›Paper›PMID 37712028›Full record

ArticleChemical science2023

Responsive calcium-derived nanoassemblies induce mitochondrial disorder to promote tumor calcification.

Yan Zhao, Xinquan Yu, Weiheng Kong, Rong-Mei Kong, Ensheng Zhang, Lian Xia, Jing Zhang, Fengli Qu, Weihong Tan

Abstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan ZhaoCollege of Chemistry and Chemical Engineering, Qufu Normal University Qufu Shandong 273165 China fengliquhn@hotmail.com.
Xinquan YuDepartment of Pathology, Cancer Hospital of Zhejiang Province, Hangzhou Institute of Medicine, Chinese Academy of Sciences Hangzhou Zhejiang 310022 China.
Weiheng KongCollege of Chemistry and Chemical Engineering, Qufu Normal University Qufu Shandong 273165 China fengliquhn@hotmail.com.
Rong-Mei KongCollege of Chemistry and Chemical Engineering, Qufu Normal University Qufu Shandong 273165 China fengliquhn@hotmail.com.ORCID https://orcid.org/0000-0002-3435-6342
Ensheng ZhangCollege of Chemistry and Chemical Engineering, Qufu Normal University Qufu Shandong 273165 China fengliquhn@hotmail.com.ORCID https://orcid.org/0000-0003-3858-733X
Lian XiaCollege of Chemistry and Chemical Engineering, Qufu Normal University Qufu Shandong 273165 China fengliquhn@hotmail.com.ORCID https://orcid.org/0000-0001-6117-7596
Jing ZhangSchool of Chemistry and Chemical Engineering, University of Jinan Jinan Shandong 250022 China.
Fengli QuCollege of Chemistry and Chemical Engineering, Qufu Normal University Qufu Shandong 273165 China fengliquhn@hotmail.com.ORCID https://orcid.org/0000-0001-6311-3051
Weihong TanDepartment of Pathology, Cancer Hospital of Zhejiang Province, Hangzhou Institute of Medicine, Chinese Academy of Sciences Hangzhou Zhejiang 310022 China.ORCID https://orcid.org/0000-0002-8066-1524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physiological calcification of the treated tumor area is considered to be a predictor of good prognosis. Promoting tumor calcification by inducing mitochondrial metabolic disorder and destroying calcium equilibrium has a potential inhibitory effect on tumor proliferation. Here, by promoting calcification by inducing mitochondrial dysfunction combined with triggering a surge of reactive oxygen species, we construct a bioresponsive calcification initiator, termed CaP-AA, using CaHPO

Identifiers

PMID37712028
PMCPMC10498499

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.