Evidence map›Paper›PMID 37711853›Full record

ArticleFrontiers in cell and developmental biology2023

Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development.

Ricardo A DeMoya, Rachel E Forman-Rubinsky, Deon Fontaine, Joseph Shin, Simon C Watkins, Cecilia W Lo, Michael Tsang

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Complex-specific HDAC1/2 regulation in the heart: insights from MiDAC disruption.American journal of physiology. Heart and circulatory physiology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ricardo A DeMoyaDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Rachel E Forman-RubinskyDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Deon FontaineDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Joseph ShinDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Simon C WatkinsDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Cecilia W LoDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Michael TsangDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Funding

Mechanism of LV Hypoplasia in Hypoplastic Left Heart Syndrome SupplementR01HL142788 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LO, CECILIA W., TSANG, MICHAEL WAIKOK · 2018 to 2021
$3.3M
Understanding the molecular mechanism of cardiomyocyte dedifferentiation and proliferation during regenerationR01HL156398 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TSANG, MICHAEL WAIKOK · 2022 to 2025
$2.2M
High-Throughput Computing for Genomics and Bioinformatics ResearchS10OD028483 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEE, ADRIAN V · 2021 to 2021
$574k
NHLBI NIH HHS R01 HL142788NHLBI NIH HHS R01 HL156398NIH HHS S10 OD028483
6 · The paper itself

Abstract

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130 kDa (

Indexed as

cardiac developmentcongenital heart diseasesecond heart fieldSIN3A/HDAC complexzebrafish

Identifiers

PMID37711853
PMCPMC10498550

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.