Evidence map›Paper›PMID 37711649›Full record

ArticleIJID regions2023

Impact of COVID-19 on hepatitis B screening in Sierra Leone: insights from a community pharmacy model of care.

Manal Ghazzawi, Lawrence S Babawo, Amir M Mohareb, Peter B James, Sahr A Yendewa, Samuel P E Massaquoi, Peterlyn E Cummings, Sulaiman Lakoh, Robert A Salata, George A Yendewa

Abstract read
In one paragraph

Article in IJID regions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manal GhazzawiKnowHep Foundation, Freetown, Sierra Leone.
Lawrence S BabawoDepartment of Nursing, School of Community Health Sciences, Njala University, Bo, Sierra Leone.
Amir M MoharebCenter for Global Health, Massachusetts General Hospital, Boston, USA.
Peter B JamesFaculty of Health, Southern Cross University, Lismore, Australia.
Sahr A YendewaMinistry of Health and Sanitation, Freetown, Sierra Leone.
Samuel P E MassaquoiMinistry of Health and Sanitation, Freetown, Sierra Leone.
Peterlyn E CummingsMinistry of Health and Sanitation, Freetown, Sierra Leone.
Sulaiman LakohMinistry of Health and Sanitation, Freetown, Sierra Leone.
Robert A SalataDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, USA.
George A YendewaDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, USA.

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
Simulation Modeling of Hepatitis B Virus Elimination Strategies in Cote d'IvoireK01AI166126 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Amir Mohareb · 2022 to 2026
$679k
NIAID NIH HHS K01 AI166126NIAID NIH HHS P30 AI060354NIAID NIH HHS U01 AI068636NIAID NIH HHS UM1 AI068636
6 · The paper itself

Abstract

Objectives: To assess the impact of COVID-19-related interruptions and seasonal patterns on hepatitis B virus (HBV) screening in a hyperendemic setting in Sierra Leone. Methods: We conducted a retrospective study of HBV testing in a community pharmacy in Freetown, Sierra Leone, from October 01, 2019, through September 30, 2022. We compared participant characteristics using Pearson's chi-square test. We evaluated trends in HBV screening and diagnosis using one-way analysis of variance with Tukey's or Dunnett's post-test. Results: Of 920 individuals screened, 161 had detectable HBV surface antigen (seroprevalence 17.5% [95% CI 14.9-20.4]). There was a 100% decrease in HBV screening during January-June of 2020; however, screening increased by 27% and 23% in the first and second years after COVID-19, respectively. Mean quarterly tests showed a significant upward trend: 55 ± 6 tests during January-March (baseline), 74 ± 16 tests during April-June, 101 ± 3 tests during July-September, and 107 ± 17 tests during October-December (one-way analysis of variance test for trend, F = 7.7, Conclusion: Community-based HBV screening dramatically improved following temporary disruptions related to COVID-19. Seasonal variation in HBV screening, but not HBV diagnosis, may have implications for HBV elimination efforts in Sierra Leone and other West African countries.

Indexed as

COVID-19DiagnosisHepatitis B virusScreeningSierra Leone

Identifiers

PMID37711649
PMCPMC10498170

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.