Evidence map›Paper›PMID 37711545›Full record

ArticleBone reports2023

Relationship between bone marrow adipose tissue and kidney function in postmenopausal women.

Sammy Badr, Anne Cotten, Romuald Mentaverri, Daniela Lombardo, Julien Labreuche, Claire Martin, Lucie Hénaut, Bernard Cortet, Julien Paccou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sammy BadrUniv. Lille, CHU Lille, MABlab ULR 4490, Department of Radiology and Musculoskeletal Imaging, F-59000 Lille, France.
Anne CottenUniv. Lille, CHU Lille, MABlab ULR 4490, Department of Radiology and Musculoskeletal Imaging, F-59000 Lille, France.
Romuald MentaverriUR UPJV 7517, Pathophysiological Mechanisms and Consequences of Cardiovascular Calcifications (MP3CV), Picardie Jules Verne University, 80025 Amiens, France.
Daniela LombardoUniv. Lille, CHU Lille, MABlab ULR 4490, Department of Rheumatology, F-59000 Lille, France.
Julien LabreucheCHU Lille, Department of Biostatistics, F-59000 Lille, France.
Claire MartinCHU Lille, Department of Biostatistics, F-59000 Lille, France.
Lucie HénautUR UPJV 7517, Pathophysiological Mechanisms and Consequences of Cardiovascular Calcifications (MP3CV), Picardie Jules Verne University, 80025 Amiens, France.
Bernard CortetUniv. Lille, CHU Lille, MABlab ULR 4490, Department of Rheumatology, F-59000 Lille, France.
Julien PaccouUniv. Lille, CHU Lille, MABlab ULR 4490, Department of Rheumatology, F-59000 Lille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bone marrow adipose tissue (BMAT) is associated with aging, osteoporosis, and chronic kidney disease (CKD). To date, the association between BMAT and kidney function in postmenopausal women has not been thoroughly investigated. The main purpose of this study was to determine whether a relationship exists between proton density fat fraction (PDFF) and kidney function in postmenopausal women. Methods: We investigated the cross-sectional association between estimated glomerular filtration rate (eGFR) - calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation - and PDFF - measured at the lumbar spine and proximal femur using Water Fat Imaging (WFI) MRI - in 199 postmenopausal women from the ADIMOS cohort study. We also performed DXA scans and laboratory measurements of sclerostin and c-terminal Fibroblast Growth Factor 23 (cFGF23). Results: Participants' mean age was 67.5 (standard deviation, SD 10.0) years. Their median eGFR was 85.0 (interquartile range, IQR 72.2-95.0) ml/min/1.73 cm Conclusion: No evidence of an association between kidney function and bone marrow adiposity was found either in the lumbar spine or proximal femur in a cohort of postmenopausal women.

Indexed as

Bone marrow adipose tissueBone mineral densityChronic kidney diseaseEstimated glomerular filtration rateOsteoporosis

Identifiers

PMID37711545
PMCPMC10498167

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.