ArticleAnnals of maxillofacial surgery
Diagnostic Challenges in a Rare Submandibular Epidermoid Cyst Transforming into Squamous Cell Carcinoma - A Case Report.
Article in Annals of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Rationale: Submandibular gland epidermoid cyst is extremely rare and malignant transformation into squamous cell carcinoma (SCC) is even rarer. No such case report is published. Patient Concerns: A 49-year-old female reported with a large, slowly growing left-sided neck swelling present for two years. Her primary concern was large swelling. Diagnosis: Clinical finding, cytology and imaging were suggestive of 'Epidermoid Cyst of Submandibular Gland'. Intraoperative frozen section and post-operative definitive histopathological examination (HPE) revealed malignant transformation into SCC. Treatment: In toto surgical excision was performed. Once the frozen section HPE confirmed transformation into SCC, clearance of 4-6 mm margin and modified supraomohyoid neck dissection was completed. Outcome: No sign of recurrence on 1-year postoperative follow-up. Take-Away Lesson: This case is unique of its kind without any previous literature report. In case of large and rapidly growing submandibular gland lesion, possibility of malignant transformation should not be overruled.
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