Evidence map›Paper›PMID 37711462›Full record

ArticleFrontiers in physiology2023

Epac induces ryanodine receptor-dependent intracellular and inter-organellar calcium mobilization in mpkCCD cells.

Kay-Pong Yip, Luisa Ribeiro-Silva, Byeong Cha, Timo Rieg, James S K Sham

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kay-Pong YipDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Luisa Ribeiro-SilvaDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Byeong ChaDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Timo RiegDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
James S K ShamDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Funding

Role of Renal and Intestinal AC6 and NHE3 for Phosphate HomeostasisR01DK110621 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI RIEG, TIMO · 2016 to 2020
$1.7M
Pharmacological Npt2a inhibition as a treatment for hyperphosphatemia in chronic kidney diseaseI01BX004968 · VA · JAMES A. HALEY VA MEDICAL CENTER · PI RIEG, TIMO · 2021 to 2024
–
BLRD VA I01 BX004968NIDDK NIH HHS R01 DK110621
6 · The paper itself

Abstract

Arginine vasopressin (AVP) induces an increase in intracellular Ca

Indexed as

aquaporin-2Epacintracellular calcium storesmitochondria-associated membraneryanodine receptor

Identifiers

PMID37711462
PMCPMC10497751

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.