ArticleCureus2023
Stellate Ganglion Block Relieves Long COVID-19 Symptoms in 86% of Patients: A Retrospective Cohort Study.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06953661 (Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome: A Randomized Double Blind Sham Placebo-controlled Pilot Study
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Stellate Ganglion Block in the Treatment of Long COVID: A Systematic Review.Current pain and headache reports · 2026Pooled it
- Intermittent fasting and a no-sugar diet for Long COVID symptoms: a randomized crossover trial.Scientific reports · 2025Trial
- Article
- Persistent prostaglandin E2 upregulation and hormonal multi-resistance: A hypothesis for long COVID.Biochemistry and biophysics reports · 2026Article
- Underuse of Pharmacologic Therapies for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Before Specialist Evaluation.Annals of family medicine · 2026Article
- Advances in the clinical application of stellate ganglion block for non-pain indications.Frontiers in medicine · 2026Review
- Stellate Ganglion Block for the Management of Long COVID Symptoms: A Retrospective Cohort Study.Cureus · 2025Article
- Multidisciplinary collaborative guidance on the assessment and treatment of patients with Long COVID: A compendium statement.PM & R : the journal of injury, function, and rehabilitation · 2025Article
- The Ganglia of the Head and Neck: Clinical Relevance for the Interventional Pain Physician.Current pain and headache reports · 2025Review
- Long-Term Neurologic Complications of COVID-19: A Practical Overview The authors present an overview of the presentation and management of common neurologic symptoms associated with long COVID.Practical neurology (Fort Washington, Pa.) · 2024Article
- Establishment of stellate ganglion block in mice.European journal of medical research · 2024Article
- Long COVID management: a mini review of current recommendations and underutilized modalities.Frontiers in medicine · 2024Review
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post-COVID-19 condition, also known as long COVID-19 syndrome and post-acute sequelae of SARS-CoV-2, encompasses an array of symptoms that persist well beyond the initial phase of the viral infection. These symptoms can range in intensity, from mild and manageable to severe and incapacitating. Due to the evolving nature of the SARS-CoV-2 pandemic, treatment protocols for the illness are in a constant state of evolution. The early stage of long COVID-19 syndrome contributes to a dearth of treatment protocols based on empirical evidence, while the absence of a conclusive pathophysiological understanding further complicates the development of such protocols. Current treatment regimens include homeopathic medicine, specialist system-focused treatments, infusion therapies, hyperbaric oxygenation, antivirals, and polypharmacy. The physiological, psychological, and societal impact of long COVID-19 cannot be approached casually and must govern the intensity with which the healthcare community approaches the treatment of long COVID-19 syndrome. In this 41-patient cohort study from a chronic pain management practice, the use of either unilateral or bilateral stellate ganglion block (SGB) was explored to manage symptoms associated with long COVID-19 syndrome. Results indicated that a substantial proportion of patients (86%) experienced a reduction of their symptoms following SGB treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.