Evidence map›Paper›PMID 37711000›Full record

ArticleEndocrine, metabolic & immune disorders drug targets2024

Effects of Sublingual Colostrum Application on Oral and Intestinal Flora of Extremely Low Birth Weight Infants.

Hua Wang, Qiu-Fang Li, Xin-Fen Xu, Xiao-Li Hu

Abstract read
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In one paragraph

Article in Endocrine, metabolic & immune disorders drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hua WangDepartment of NICU, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Qiu-Fang LiDepartment of nursing, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Xin-Fen XuDepartment of nursing, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Xiao-Li HuDepartment of obstetrics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.

Funding

Medical and Heath Technology Program of Zhejiang Province 2022RC041, 2021KY 769
6 · The paper itself

Abstract

backgroundThe aim of this study is to analyze the effects of colostrum application on the establishment of normal flora in the intestinal tracts and oral cavities of extremely low birth weight infants (ELBWI).

methodsA prospective cohort study design was adopted following the STROBE guidelines (Supplementary File 1). Colostrum was administered immediately after obtaining maternal breast milk using a special sterile cotton swab. There were no specific treatments for infants who did not receive colostrum. This experiment was completed on day 5 post-birth and the patients were divided into the colostrum and control groups, corresponding to whether or not colostrum was administered. Throat swabs and stool samples were collected on days 1 and 5 post-birth.

resultsUsing the conventional bacteria cultivation technique, the detection rate of bacteria in 98 cases of meconium at birth was 15.31%. On day 5, the detection rates of

conclusionColostrum application had limited effects on intestinal flora colonization but contributes to physiological oral flora colonization.

Indexed as

ColostrumGastrointestinal MicrobiomeInfant, Extremely Low Birth WeightFemaleHumansInfant, NewbornMaleMouthPregnancyProspective StudiesBacteria culturecolostrumelbwiintestinal flora.meconiumsublingual mucosal

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.