Evidence map›Paper›PMID 37710294›Full record

ReviewBiology direct2023

Biological roles of RNA m7G modification and its implications in cancer.

Xin Zhang, Wen-Yan Zhu, Shu-Yi Shen, Jia-Hao Shen, Xiao-Dong Chen

Abstract readReview
In one paragraph

Review in Biology direct, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. The cellular landscape of druggable RNA-binding proteins.Nature reviews. Drug discovery · 2026
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  3. Beyond mBiomedicines · 2026
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  8. Targeting intracellular mRNA mJournal of advanced research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xin Zhang *Department of Dermatology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Wen-Yan Zhu *Department of Dermatology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Shu-Yi Shen *Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Jia-Hao ShenDepartment of Dermatology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Xiao-Dong ChenDepartment of Dermatology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China. dermatochen@ntu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

M7G modification, known as one of the common post-transcriptional modifications of RNA, is present in many different types of RNAs. With the accurate identification of m7G modifications within RNAs, their functional roles in the regulation of gene expression and different physiological functions have been revealed. In addition, there is growing evidence that m7G modifications are crucial in the emergence of cancer. Here, we review the most recent findings regarding the detection techniques, distribution, biological functions and Regulators of m7G. We also summarize the connections between m7G modifications and cancer development, drug resistance, and tumor microenvironment as well as we discuss the research's future directions and trends.

Indexed as

NeoplasmsHumansRNATumor MicroenvironmentRNACarcinomaImmune microenvironmentN7-methylguanosineRNA methylation modification

Identifiers

PMID37710294
PMCPMC10500781

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.