ArticleJournal of orthopaedic surgery and research2023
Association between dietary folate intake and bone mineral density in a diverse population: a cross-sectional study.
Article in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 11 citations in OpenAlex.
- The gut-bone axis: microbial metabolism and nutritional interventions for bone health.Gut microbes · 2026Review
- Folate deficiency and total shoulder arthroplasty outcomes.Shoulder & elbow · 2026Article
- The role of B-vitamin intake, B-vitamin-rich dietary patterns, the B-vitamin deficiency index in bone mineral density among school-aged children.Pediatric research · 2026Article
- The gut-bone axis: impact of diet on gut microbiome and osteoporosis.Bone research · 2026Review
- Article
- Effects of Freeze-Dried Sake Lees and Rice Koji Extract on Osteoporosis in a Postmenopausal Mouse Model.Nutrients · 2025Article
- Article
- Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.Frontiers in endocrinology · 2025Article
- Improvement of serum folate status in the US women of reproductive age with fortified iodised salt with folic acid (FISFA study).Public health nutrition · 2024Article
- Association between dietary folate intake and the risk of osteoporosis in adults: a cross-sectional study.BMC musculoskeletal disorders · 2024Article
- Nutrition-Based Support for Osteoporosis in Postmenopausal Women: A Review of Recent Evidence.International journal of women's health · 2024Review
- Impact of Folate Intake on Bone Mineral Density in Patients with Inflammatory Bowel Disease.Nutrients · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundOsteoporosis is a major public health problem, yet the association between dietary folate intake and bone health has been rarely studied. This study aimed to investigate the relationship between dietary folate intake and bone mineral density (BMD) in the general population of the USA.
methodsUtilizing data from the National Health and Nutrition Examination Survey, dietary folate intake was gauged through 24-h dietary recall and BMD was determined via dual-energy X-ray absorptiometry. Multivariate linear regression models and generalized additive models were employed for correlation analysis.
resultsThe study incorporated 9839 participants (48.88% males, aged 20-85 years, mean age: 47.62 ± 16.22). The average dietary folate intake stood at 401.1 ± 207.9 μg/day. And the average total femur, femoral neck, trochanter, intertrochanter, and lumbar BMD were 0.98 ± 0.16 g/cm
conclusionIn summary, our study reveals a significant positive association between dietary folate intake and BMD, across different age groups and particularly among individuals over 80 years old. Non-Hispanic whites benefit the most from increased folate intake. Physical activity level and serum 25-hydroxyvitamin D levels interact with this association. Screening and early intervention for osteoporosis may be essential for individuals with low dietary folate intake.
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