ArticleBMC neurology2023
Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults.
Article in BMC neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Inadequate sleep increases stroke risk: evidence from a comprehensive meta-analysis of incidence and mortality.GeroScience · 2025Pooled it
- Exploring the Active Ingredients and Core Targets of Erxia Decoction in the Treatment of Sleep Disorder by Integration of Network Pharmacology and Proteomics.Combinatorial chemistry & high throughput screening · 2026Article
- Biological ageing, diet quality, and stroke: evidence from two population-based studies and an exploratory hospital-based Chinese cross-sectional dataset.Frontiers in nutrition · 2026Article
- Sleep Stage Monitoring in Congenital Heart Disease (CHD) Using a Digital Health Application Programming Interface (API).Journal of clinical medicine · 2025Article
- Supine sleep position and angina frequency: an analysis from the sleep heart health study.Sleep & breathing = Schlaf & Atmung · 2025Article
- Sleep and Stroke-An Overlooked Bidirectional Influence: Why Should Sleep and Vascular Neurologists Work Closer?Journal of clinical medicine · 2025Article
- Association of Income Inequality and Sleep Duration With Cardiovascular Outcomes in China and the UK.JACC. Asia · 2025Article
- Sarcopenia Is Associated With Increased Risk of Abnormal Sleep Duration in the Older People: A 10-Year Cohort Study From China.Journal of cachexia, sarcopenia and muscle · 2025Article
- Associations of reallocating sedentary leisure-time to alternative discretionary movement behaviours with incident cardiometabolic diseases in 0.5 million Chinese adults.The Lancet regional health. Western Pacific · 2025Article
- Comparative analysis of sleep duration and stroke prevalence in China and the U.S. before and during COVID-19.Journal of cardiothoracic surgery · 2025Article
- Review
- Associations of physical activity and sedentary behavior with insomnia in middle-aged and older adults: a cross-sectional study.Frontiers in public health · 2025Article
- Clinical effects of acupuncture treatment for prevention of insomnia-induced stroke: A large-scale cohort study.Journal of traditional and complementary medicine · 2025Article
- Mineralocorticoid Receptor and Sleep Quality in Chronic Kidney Disease.International journal of molecular sciences · 2024Review
- The link between sleep duration and stroke risk.Brain circulationArticle
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThere is uncertainty about the optimum sleep duration for risk of different subtypes of stroke and ischaemic heart disease.
methodsThe present analyses involved 409,156 adults in the China Kadoorie Biobank study without a prior history of coronary heart disease or stroke or insomnia symptoms. The mean age of study participants was 52 years and 59% were women. Self-reported sleep duration including daytime napping was recorded using a questionnaire. The adjusted hazard ratios (HRs) for disease outcomes associated with sleep duration were estimated by Cox proportional hazards after adjustment for confounding factors.
resultsThe overall mean (SD) sleep duration was 7.4 (1.4) hours. The associations of sleep duration with CVD types were U-shaped, with individuals reporting 7-8 h of sleep having the lowest risks. Compared with those who typically slept 7-8 h, individuals with very short sleep duration (≤ 5 h) had adjusted HRs of 1.10 (95% CI 1.04-1.16), 1.07 (1.01-1.13), 1.19 (1.06-1.33) and 1.23 (1.10-1.37) for total stroke, ischaemic stroke (IS), Intracerebral haemorrhage (ICH) and major coronary events (MCE), respectively. Likewise, individuals with very long sleep duration (≥ 10 h) had HRs of 1.12 (1.07-1.17), 1.08 (1.03-1.14), 1.23 (1.12-1.35) and 1.22 (1.10-1.34) for the same diseases, respectively, with little differences by sex and age. The patterns were similar for all-cause mortality.
conclusionsWhile abnormal sleep duration (≤ 6 h or ≥ 9 h) was associated with higher risks of CVD, the risks were more extreme for those reporting ≤ 5 or ≥ 10 h, respectively and such individuals should be prioritised for more intensive treatment for CVD prevention.
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