ArticleScientific reports2023
Formation of vesicular structures from fatty acids formed under simulated volcanic hydrothermal conditions.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The Origin of Life and Cellular Systems: A Continuum from Prebiotic Chemistry to Biodiversity.Life (Basel, Switzerland) · 2025Article
- A scope of prebiotic neat reaction conditions and the mechanism of urea-assisted phosphorylations of alcohols.Nature communications · 2025Article
- Chemiosmotic ATP synthesis by minimal protocells.Cell reports. Physical science · 2025Article
- From Zero to Hero: The Cyanide-Free Formation of Amino Acids and Amides from Acetylene, Ammonia and Carbon Monoxide in Aqueous Environments in a Simulated Hadean Scenario.Life (Basel, Switzerland) · 2024Article
- Nickel-organo compounds as potential enzyme precursors under simulated early Earth conditions.Communications chemistry · 2024Article
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Authors and funding
10 authors.
Funding
Abstract
Microscopic compartmentalization is beneficial in synthetic chemistry and indispensable for the evolution of life to separate a reactive "inside" from a hydrolyzing "outside". Here, we show compartmentalization in aqueous solution containing mixtures of fatty acids up to 19 carbon atoms which were synthesized by one-pot reactions of acetylene and carbon monoxide in contact with nickel sulfide at 105 °C, reaction requirements which are compatible to Hadean Early Earth conditions. Based on confocal, dynamic light scattering (DLS) and transmission electron microscopy (TEM) measurements, vesicle-like structures with diameters of 10-150 nm are formed after solvent extraction and resolubilisation. Moreover fluorescent dye was encapsulated into the structures proving their vesicular properties. This self-assembly could also have occurred on Early Earth as a crucial step in establishing simple membranes of proto-cells as a prerequisite in the evolution of metabolism and life.
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Registered trials
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