Evidence map›Paper›PMID 37709944›Full record

Trial reportEuropean journal of nutrition2024

Snack quality and snack timing are associated with cardiometabolic blood markers: the ZOE PREDICT study.

Kate M Bermingham, Anna May, Francesco Asnicar, Joan Capdevila, Emily R Leeming, Paul W Franks, Ana M Valdes, Jonathan Wolf, George Hadjigeorgiou, Linda M Delahanty and 3 more

3 registry-linked trialsAbstract readClinical Trial
In one paragraph

Trial report in European journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03479866 naunknown statusnot on this map

Predicting Inter-individual Differences in Biochemical and Behavioral Response to Meals With Different Nutritional Compositions Using Metabolomic and Microbiome Profiling.

TypeinterventionalSponsorGuy's and St Thomas' NHS Foundation TrustRan2018 to 2023Enrolled2,500ConditionsDiabetes, Heart Diseases, Diet Habit, Diet ModificationArmsDietary intervention
NCT07776418 narecruitingnot on this mapstarted 2026, after this paper: background citation

The ZOE SMART EATS (Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks) Acute Postprandial Study: Investigating the Acute Effects of a High-fibre Plant-based Snack Bar on Subjective Postprandial Hunger, Energy Intake and Eating Behaviour in Healthy UK Adults.

TypeinterventionalSponsorZoe Global LimitedRan2026 to 2026Enrolled54ConditionsHealthy Participants, Healthy Adult Subject, Healthy Subjects, Healthy Adult VolunteerArmsHigh-fibre plant-based snack bar, Control snack bars
NCT07782593 narecruitingnot on this mapstarted 2026, after this paper: background citation

The ZOE SMART EATS (Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks) Chronic Randomised Controlled Trial: Investigating the Chronic Effects of a High-fibre Plant-based Snack Bar on Subjective Daily Hunger, the Gut Microbiome and Gastrointestinal Symptoms in Healthy UK Adults.

TypeinterventionalSponsorZoe Global LimitedRan2026 to 2026Enrolled100ConditionsHealthy Participants, Healthy Adult Subject, Healthy Subjects, Healthy Adult VolunteerArmsHigh-fibre plant-based snack bar, Control snack bars
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Goals in Nutrition Science 2025-2030.Frontiers in nutrition · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kate M Bermingham *Department of Nutritional Sciences, King's College London, London, UK.
Anna May *ZOE Ltd, London, UK.
Francesco AsnicarDepartment CIBIO, University of Trento, Trento, Italy.
Joan CapdevilaZOE Ltd, London, UK.
Emily R LeemingDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Paul W FranksDepartment of Clinical Sciences, Lund University, Malmö, Sweden.
Ana M ValdesSchool of Medicine, University of Nottingham, Nottingham, UK.
Jonathan WolfZOE Ltd, London, UK.
George HadjigeorgiouZOE Ltd, London, UK.
Linda M DelahantyDiabetes Center, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Nicola SegataDepartment CIBIO, University of Trento, Trento, Italy.
Tim D SpectorDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Sarah E Berry *Department of Nutritional Sciences, King's College London, London, UK. sarah.e.berry@kcl.ac.uk.ORCID http://orcid.org/0000-0002-5819-5109

Funding

New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Medical Research Council MR/W026813/1NIDDK NIH HHS P30 DK111022Wellcome Trust
6 · The paper itself

Abstract

backgroundSnacking is a common diet behaviour which accounts for a large proportion of daily energy intake, making it a key determinant of diet quality. However, the relationship between snacking frequency, quality and timing with cardiometabolic health remains unclear.

designDemography, diet, health (fasting and postprandial cardiometabolic blood and anthropometrics markers) and stool metagenomics data were assessed in the UK PREDICT 1 cohort (N = 1002) (NCT03479866). Snacks (foods or drinks consumed between main meals) were self-reported (weighed records) across 2-4 days. Average snacking frequency and quality [snack diet index (SDI)] were determined (N = 854 after exclusions). Associations between snacking frequency, quality and timing with cardiometabolic blood and anthropometric markers were assessed using regression models (adjusted for age, sex, BMI, education, physical activity level and main meal quality).

resultsParticipants were aged (mean, SD) 46.1 ± 11.9 years, had a mean BMI of 25.6 ± 4.88 kg/m

conclusionSnack quality and timing of consumption are simple diet features which may be targeted to improve diet quality, with potential health benefits. CLINICAL TRIAL REGISTRY NUMBER AND WEBSITE: NCT03479866, https://clinicaltrials.gov/ct2/show/NCT03479866?term=NCT03479866&draw=2&rank=1.

Indexed as

Cardiovascular DiseasesSnacksAdultDietEnergy IntakeFeeding BehaviorFemaleGlycated HemoglobinHumansMaleMiddle AgedGlycated HemoglobinCardiometabolic healthFrequencyQualityQuantitySnackingTiming

Identifiers

PMID37709944
PMCPMC10799113

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.