Evidence map›Paper›PMID 37709729›Full record

ArticleBiomacromolecules2023

Self-Immolative Polymer Nanoparticles with Precise and Controllable pH-Dependent Degradation.

Samuel A Smith, Bruna Rossi Herling, Changhe Zhang, Maximilian A Beach, Serena L Y Teo, Elizabeth R Gillies, Angus P R Johnston, Georgina K Such

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Synthesis,ACS omega · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samuel A SmithDepartment of Chemistry, The University of Melbourne, Parkville, Victoria 3010, Australia.
Bruna Rossi HerlingMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3010, Australia.
Changhe ZhangDepartment of Chemistry, The University of Melbourne, Parkville, Victoria 3010, Australia.
Maximilian A BeachDepartment of Chemistry, The University of Melbourne, Parkville, Victoria 3010, Australia.
Serena L Y TeoMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3010, Australia.
Elizabeth R GilliesDepartment of Chemistry and Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, Ontario N6A 5B7, Canada.ORCID 0000-0002-3983-2248
Angus P R JohnstonMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3010, Australia.ORCID 0000-0001-5611-4515
Georgina K SuchDepartment of Chemistry, The University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0002-2868-5799

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymer nanoparticles have generated significant interest as delivery systems for therapeutic cargo. Self-immolative polymers (SIPs) are an interesting category of materials for delivery applications, as the characteristic property of end-to-end depolymerization allows for the disintegration of the delivery system, facilitating a more effective release of the cargo and clearance from the body after use. In this work, nanoparticles based on a pH-responsive polymer poly(ethylene glycol)-

Indexed as

NanoparticlesPolymersDrug Delivery SystemsHydrogen-Ion ConcentrationPolyethylene GlycolsPolyethylene GlycolsPolymers

Identifiers

PMID37709729
PMCPMC10649787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.