COVID-19 Serological Study in Non-infected Vaccinated Subjects: Differences among Age, Sex, and Vaccine Brand.

Yaniré Castro-Torres, Estela S Estapé, María T San Martín, Deana Hallman

Abstract read

In one paragraph

Article in Puerto Rico health sciences journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yaniré Castro-TorresMasters in Clinical Laboratory Sciences; Owner, Colon Clinical Laboratories, Puerto Rico.

Estela S EstapéProfessor and Director, Research Center, San Juan Bautista School of Medicine and Senior Advisor, Postdoctoral Master of Science in Clinical & Translational Research, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.

María T San MartínAssociate Professor, School of Health Professions, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.

Deana HallmanAssistant Professor of Medicine, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.

Funding

Tracking and Evaluation CoreU54GM133807 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LUCIANO, CARLOS A., MOROU-BERMUDEZ, EVANGELIA · 2020 to 2024

$17.7M

NIGMS NIH HHS U54 GM133807

6 · The paper itself

Abstract

objectiveTo evaluate IgG antibody levels against SARS-CoV-2 in non-infected vaccinated subjects among vaccine brand, sex, and age.

methodsAbbott's AdviseDx SARS-CoV-2 IgG II immunoassay was used to measure IgG levels within 6-9 months after the second dose vaccination; level >50 AU/mL was classified as a positive test.

resultsData of 183 non-infected vaccinated subjects was analyzed according to the vaccine brand, time after second vaccination, sex, and age. Bivariate analysis showed that receiving the Moderna brand vaccine, being female, and younger were associated with higher antibody levels, p<.001. Conversely, no differences were observed between the IgG antibody levels against SARS-CoV-2 and time after second vaccination (6-7 months as compared to 8-9 months), p=.49.

conclusionAfter six to nine months post-vaccination, receiving the Moderna vaccine, being female, and being younger were significantly associated to higher IgG antibody levels to SARS-CoV-2 in non-infected vaccinated subjects.

Indexed as

COVID-19VaccinesFemaleHumansImmunoglobulin GMaleSARS-CoV-2VaccinationImmunoglobulin GVaccinesCOVID-19 antibodiesCOVID-19 antibodies postvaccinationSARS-CoV-2 antibodies

Identifiers

PMID37709676

PMCPMC11302121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.