ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023
Biostatistical Estimation of Tau Threshold Hallmarks (BETTH) Algorithm for Human Tau PET Imaging Studies.
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Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
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Who cites it
17 citing papers in PubMed, 18 citations in OpenAlex.
- Correlation between in vivoAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Continuum of Core 1 biomarkers in preclinical Alzheimer's disease.Alzheimer's research & therapy · 2026Article
- Plasma amyloid-β predicts amyloid-β accumulation in PET A- non-demented participants.Journal of Alzheimer's disease : JAD · 2026Article
- Head-to-head comparison of plasma p-tau217 immunoassays for incipient Alzheimer's disease in community cohorts.Alzheimer's research & therapy · 2026Article
- Head-to-head comparison of plasma p-tau217 immunoassays for incipient Alzheimer's disease in community cohorts.Research square · 2025Article
- Head-to-head comparison of plasma p-tau217 immunoassays for incipient Alzheimer's disease in community cohorts.medRxiv : the preprint server for health sciences · 2025Article
- Cross-cohort validation and cutpoint estimation of the Janssen plasma p-tau217+ assay in predominantly cognitively normal community cohorts.medRxiv : the preprint server for health sciences · 2025Article
- Plasma biomarkers identify brain ATN abnormalities in a dementia-free population-based cohort.Alzheimer's research & therapy · 2025Article
- Comparison of visual and analytic methods of Alzheimer's disease pathologic staging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Tau Imaging: Use and Implementation in New Diagnostic and Therapeutic Paradigms for Alzheimer's Disease.Geriatrics (Basel, Switzerland) · 2025Review
- The Taiwan-ADNI workflow toward integrating plasma p-tau217 into prediction models for the risk of Alzheimer's disease and tau burden.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Kinetic modeling of the monoamine oxidase-B radioligand [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease.Molecular neurodegeneration · 2024Article
- Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease.medRxiv : the preprint server for health sciences · 2024Article
- Implementation and Assessment of Tau Thresholds in Non-Demented Individuals as Predictors of Cognitive Decline in Tau Imaging Studies.Journal of Alzheimer's disease : JAD · 2024Article
- The LATTICE Study: Design of a pilot feasibility randomized controlled trial of lithium to delay cognitive decline in mild cognitive impairment.Alzheimer's & dementia (New York, N. Y.)Article
- CenTauR: Toward a universal scale and masks for standardizing tau imaging studies.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
19 authors at 3 institutions in 2 countries.
Alexandra GogolaDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania; alexandra-gogola@pitt.edu.
Brian J LoprestiDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Dana TudorascuDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Beth SnitzDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Davneet MinhasDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Vincent DoréDepartment of Molecular Imaging and Therapy, Austin Health, Melbourne, Victoria, Australia.
Milos D IkonomovicDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
C Elizabeth ShaabanDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Cristy MatanDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Pierrick BourgeatHealth and Biosecurity, Commonwealth Scientific and Industrial Research Organisation, Melbourne, Victoria, Australia.
N Scott MasonDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Howard AizensteinDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Chester A MathisDepartment of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
William E KlunkDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Christopher C RoweDepartment of Molecular Imaging and Therapy, Austin Health, Melbourne, Victoria, Australia.
Oscar L LopezDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Ann D CohenDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Victor L VillemagneDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Alzheimer’s Disease Neuroimaging Initiative
University of Pittsburgh · USCommonwealth Scientific and Industrial Research Organisation · AUAustin Health · AU
Funding
Vascular Moderators of the Impact of Alzheimer's Pathology in the Young-OldP01AG025204 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Ann D. Cohen · 2005 to 2026
$56.5MTREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAMBOH, M. ILYAS · 1985 to 2019
$43.0MResearch Education ComponentP30AG066468 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI C. Elizabeth Shaaban · 2020 to 2026
$29.4MRoles of Gray Matter Brain Aging and Small Vessel Disease in AD PathophysiologyRF1AG025516 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AIZENSTEIN, HOWARD J, VILLEMAGNE, VICTOR LUIS · 2014 to 2021
$9.0MRole of midlife cardiovascular disease on Alzheimer’s Pathology and cerebrovascular reactivity in the young-old.R01AG052446 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COHEN, ANN D. · 2016 to 2020
$3.7MAlzheimer neuroimaging-biomarkers in pre-clinical cognitive decline from a population-based studyR01AG052521 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SNITZ, BETH · 2016 to 2020
$3.3MPopulation neuroscience of sex differences in the Alzheimer's disease biomarker cascade: The role of cerebral small vessel diseaseK01AG071849 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI C. Elizabeth Shaaban · 2022 to 2026
$629kNIA NIH HHS K01 AG071849NIA NIH HHS P01 AG025204NIA NIH HHS P30 AG066468NIA NIH HHS P50 AG005133NIA NIH HHS R01 AG052446NIA NIH HHS R01 AG052521NIA NIH HHS RF1 AG025516
Abstract
A methodology for determining tau PET thresholds is needed to confidently detect early tau deposition. We compared multiple threshold-determining methods in participants who underwent either
Indexed as
Alzheimer DiseaseCognitive DysfunctionAmyloid beta-PeptidesBrainCarbolinesHumansMiddle AgedPositron-Emission Tomographytau ProteinsAmyloid beta-PeptidesCarbolinestau Proteins18F-flortaucipir18F-MK-6240Alzheimer diseasePETtau
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.