Evidence map›Paper›PMID 37709302›Full record

ArticleBMJ health & care informatics2023

Long short-term memory model identifies ARDS and in-hospital mortality in both non-COVID-19 and COVID-19 cohort.

Jen-Ting Chen, Rahil Mehrizi, Boudewijn Aasman, Michelle Ng Gong, Parsa Mirhaji

Abstract read
In one paragraph

Article in BMJ health & care informatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Jen-Ting ChenDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, UCSF, San Francisco, California, USA tina.chen@ucsf.edu.ORCID http://orcid.org/0000-0002-8530-2520
Rahil MehriziDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
Boudewijn AasmanCenter for Health Data Innovations, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
Michelle Ng GongDepartment of Medicine, Division of Critical Care Medicine, Montefiore Medical Center, Bronx, New York, USA.
Parsa MirhajiDepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA.

Funding

Einstein-Montefiore Clinical and Translational Science Award HubUM1TR004400 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Jessica Kahn, Mimi Y Kim · 2023 to 2026
$17.3M
TREAT ECARDS: Translating Evidence into Action: Electronic Clinical Decision Support in ARDSR18HS026188 · AHRQ · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI GONG, MICHELLE NG · 2018 to 2020
$1.2M
AHRQ HHS R18 HS026188NCATS NIH HHS UM1 TR004400
6 · The paper itself

Abstract

objectiveTo identify the risk of acute respiratory distress syndrome (ARDS) and in-hospital mortality using long short-term memory (LSTM) framework in a mechanically ventilated (MV) non-COVID-19 cohort and a COVID-19 cohort.

methodsWe included MV ICU patients between 2017 and 2018 and reviewed patient records for ARDS and death. Using active learning, we enriched this cohort with MV patients from 2016 to 2019 (MV non-COVID-19, n=3905). We collected a second validation cohort of hospitalised patients with COVID-19 in 2020 (COVID+, n=5672). We trained an LSTM model using 132 structured features on the MV non-COVID-19 training cohort and validated on the MV non-COVID-19 validation and COVID-19 cohorts.

resultsApplying LSTM (model score 0.9) on the MV non-COVID-19 validation cohort had a sensitivity of 86% and specificity of 57%. The model identified the risk of ARDS 10 hours before ARDS and 9.4 days before death. The sensitivity (70%) and specificity (84%) of the model on the COVID-19 cohort are lower than MV non-COVID-19 cohort. For the COVID-19 + cohort and MV COVID-19 + patients, the model identified the risk of in-hospital mortality 2.4 days and 1.54 days before death, respectively. DISCUSSION: Our LSTM algorithm accurately and timely identified the risk of ARDS or death in MV non-COVID-19 and COVID+ patients. By alerting the risk of ARDS or death, we can improve the implementation of evidence-based ARDS management and facilitate goals-of-care discussions in high-risk patients.

conclusionUsing the LSTM algorithm in hospitalised patients identifies the risk of ARDS or death.

Indexed as

COVID-19Respiratory Distress SyndromeAlgorithmsHospital MortalityHumansNeural Networks, ComputerCOVID-19Critical Care OutcomesDecision Support Systems, ClinicalMedical Informatics

Identifiers

PMID37709302
PMCPMC10503386

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.