Evidence map›Paper›PMID 37708209›Full record

ArticlePloS one2023

Prediction of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer by using a deep learning model with 18F-FDG PET/CT.

Gülcan Bulut, Hasan Ikbal Atilgan, Gökalp Çınarer, Kazım Kılıç, Deniz Yıkar, Tuba Parlar

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. [Artificial intelligence in predicting pathological complete response to neoadjuvant chemotherapy for breast cancer: current advances and challenges].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gülcan BulutDivision of Medical Oncology, International Medicana Hospital, Izmir, Turkey.ORCID 0000-0001-7382-0972
Hasan Ikbal AtilganDepartment of Nuclear Medicine, Mustafa Kemal University Medical School, Hatay, Turkey.
Gökalp ÇınarerDepartment of Computer Engineering, Faculty of Engineering and Architecture, Bozok University, Yozgat, Turkey.
Kazım KılıçDepartment of Computer Programming, Yozgat Vocational High School, Bozok University, Yozgat, Turkey.
Deniz YıkarDivision of Nuclear Medicine, Hatay Training and Research Hospital, Hatay, Turkey.
Tuba ParlarDepartment of Computer Technologies, Mustafa Kemal University, Hatay, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study is 18F-FDG PET/CT imaging by using deep learning method are predictive for pathological complete response pCR after Neoadjuvant chemotherapy (NAC) in locally advanced breast cancer (LABC).

introductionNAC is the standard treatment for locally advanced breast cancer (LABC). Pathological complete response (pCR) after NAC is considered a good predictor of disease-free survival (DFS) and overall survival (OS).Therefore, there is a need to develop methods that can predict the pCR at the time of diagnosis.

methodsThis article was designed as a retrospective chart study.For the convolutional neural network model, a total of 355 PET/CT images of 31 patients were used. All patients had primary breast surgery after completing NAC.

resultsPathological complete response was obtained in a total of 9 patients. The study results show that our proposed deep convolutional neural networks model achieved a remarkable success with an accuracy of 84.79% to predict pathological complete response.

conclusionIt was concluded that deep learning methods can predict breast cancer treatment.

Indexed as

Breast NeoplasmsDeep LearningFemaleFluorodeoxyglucose F18HumansNeoadjuvant TherapyPositron Emission Tomography Computed TomographyRetrospective StudiesFluorodeoxyglucose F18

Identifiers

PMID37708209
PMCPMC10501592

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.