Evidence map›Paper›PMID 37708123›Full record

Observational studyPloS one2023

Prevalence and knowledge about acute mountain sickness in the Western Alps.

Marc Moritz Berger, Anika Hüsing, Nicolai Niessen, Lisa Maria Schiefer, Michael Schneider, Peter Bärtsch, Karl-Heinz Jöckel

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06446427 (The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06446427 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2024 to 2025Enrolled20ConditionsHigh Altitude, Hypobaric Hypoxia, Risk ReductionArmsAcute high altitude exposure, Acute high altitude exposure, with supplementary oxygen, Subacute high altitude exposure, after having spent a night at high altitude
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. [Body Function Changes and Prevention Strategies in High-Altitude Environment].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  10. Article
  11. Altitude illnesses.Nature reviews. Disease primers · 2024
    Review
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marc Moritz BergerDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany.ORCID 0000-0001-6771-3193
Anika HüsingInstitute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany.
Nicolai NiessenDepartment of Internal Medicine, Klinikum Garmisch-Partenkirchen, Garmisch-Partenkirchen, Germany.
Lisa Maria SchieferParacelsus Medical University, Salzburg, Austria.
Michael SchneiderInstitute for Health Services Research and Clinical Epidemiology, Philipps-Universitaet Marburg, Marburg, Germany.
Peter BärtschDepartment of Internal Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Karl-Heinz JöckelInstitute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the prevalence of acute mountain sickness (AMS) in 1370 mountaineers at four different altitudes in the Western Alps. We also examined the influence of potential risk factors and the knowledge about AMS on its prevalence.

methodsIn this observational cross-sectional study AMS was assessed on the day of ascent by the Lake Louise score (LLS, cut-off ≥3, version 2018) and the AMS-Cerebral (AMS-C) score of the environmental symptom questionnaire (cut-off ≥0,70). The latter was also obtained in the next morning. Knowledge regarding AMS and high-altitude cerebral edema (HACE) and the potential risk factors for AMS were evaluated by questionnaires.

resultsOn the day of ascent, the prevalence of AMS assessed by the LLS and AMS-C score was 5.8 and 3.9% at 2850 m, 2.1 and 3.1% at 3050 m, 14.8 and 10.1% at 3650 m, and 21.9 and 15% at 4559 m, respectively. The AMS prevalence increased overnight from 10.1 to 14.5% and from 15 to 25.2% at 3650 m and 4559 m, respectively, and was unchanged at 2850 m and 3050 m. A history of AMS, higher altitude, lower degree of pre-acclimatization, and younger age were identified as risk factors for developing AMS. Slow ascent was weakly associated with AMS prevalence, and sex and knowledge about AMS and HACE were indistinct.

conclusionAMS is common at altitudes ≥ 3650 m and better knowledge about AMS and HACE was not associated with less AMS in mountaineers with on average little knowledge.

Indexed as

Altitude SicknessAcute DiseaseAltitudeHumansPrevalenceRisk Factors

Identifiers

PMID37708123
PMCPMC10501682

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.