Evidence map›Paper›PMID 37708025›Full record

ArticleCell reports2023

A neuron-specific interaction between Alzheimer's disease risk factors SORL1, APOE, and CLU.

Pranav Preman, Amaia M Arranz

Open access · goldAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Pranav PremanVIB Center for Brain & Disease Research, Leuven, Belgium; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven (University of Leuven), Leuven, Belgium.
Amaia M ArranzAchucarro Basque Center for Neuroscience, Leioa, Spain; Ikerbasque Basque Foundation for Science, Bilbao, Spain. Electronic address: amaia.arranz@achucarro.org.
Ikerbasque · ESVIB-KU Leuven Center for Brain & Disease Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lee et al.

Indexed as

Alzheimer DiseaseApolipoproteins EClusterinLDL-Receptor Related ProteinsMembrane Transport ProteinsNeuronsAmyloid beta-PeptidesAnimalsAutophagyHumansRisk Factorstau ProteinsAmyloid beta-PeptidesApolipoproteins ECLU protein, humanClusterinLDL-Receptor Related ProteinsMembrane Transport ProteinsSORL1 protein, humantau ProteinsCP: Neuroscience

Identifiers

PMID37708025
OpenAlexW4386712213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.