ArticleCell reports2023
Top-down input modulates visual context processing through an interneuron-specific circuit.
Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed.
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- Intrinsic timing, not temporal prediction, underlies ramping dynamics in visual and parietal cortex during passive behavior.Science advances · 2026Article
- Cell-Type-Specific Synaptic Scaling Mechanisms Differentially Contribute to Associative Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Disinhibitory signaling enables flexible coding of top-down information in cortical networks.PLoS biology · 2026Article
- Psychedelics relax predictive processing in the post-acute period by remodeling cortico-cortical feedback circuits.bioRxiv : the preprint server for biology · 2026Article
- Ontology-constrained multi-LLM scoring of hypothesis support in the predictive processing literature.Research square · 2026Article
- A shared predictive architecture in the sensory cortex for statistical and reward-based learning.Current opinion in neurobiology · 2026Review
- A Key Regulator of Dendritic Morphology in Supragranular Neocortex Impacts Mismatch Negativity.bioRxiv : the preprint server for biology · 2026Article
- Global context rapidly shapes sensory responses in V1.bioRxiv : the preprint server for biology · 2026Article
- Cortical deviance detection represents a canonical difference signal.bioRxiv : the preprint server for biology · 2026Article
- Article
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- Feature selective inhibitory mechanisms enable expectation suppression in cortical microcircuits.Scientific reports · 2025Article
- Learning-dependent cholinergic plasticity reconfigures cortical circuit dynamics.bioRxiv : the preprint server for biology · 2025Article
- Mismatch negativity develops in adolescence and independently of microglia.bioRxiv : the preprint server for biology · 2025Article
- Altered oscillatory coupling reflects possible inhibitory interneuron dysfunction in Rett syndrome.medRxiv : the preprint server for health sciences · 2025Article
- A genetic algorithm for self-supervised models of oscillatory neurodynamics.bioRxiv : the preprint server for biology · 2025Article
- Duet model unifies diverse neuroscience experimental findings on predictive coding.bioRxiv : the preprint server for biology · 2025Article
- Neural signature of chronic migraine mice model and related photophobia in the primary visual cortex.The journal of headache and pain · 2025Article
- A hierarchical multiscale model of forward and backward alpha-band traveling waves in the visual system.PLoS computational biology · 2025Article
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8 authors.
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Abstract
Visual stimuli that deviate from the current context elicit augmented responses in the primary visual cortex (V1). These heightened responses, known as "deviance detection," require local inhibition in the V1 and top-down input from the anterior cingulate area (ACa). Here, we investigated the mechanisms by which the ACa and V1 interact to support deviance detection. Local field potential recordings in mice during an oddball paradigm showed that ACa-V1 synchrony peaks in the theta/alpha band (≈10 Hz). Two-photon imaging in the V1 revealed that mainly pyramidal neurons exhibited deviance detection, while contextually redundant stimuli increased vasoactive intestinal peptide (VIP)-positive interneuron (VIP) activity and decreased somatostatin-positive interneuron (SST) activity. Optogenetic drive of ACa-V1 inputs at 10 Hz activated V1-VIPs but inhibited V1-SSTs, mirroring the dynamics present during the oddball paradigm. Chemogenetic inhibition of V1-VIPs disrupted Aca-V1 synchrony and deviance detection in the V1. These results outline temporal and interneuron-specific mechanisms of top-down modulation that support visual context processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.