Evidence map›Paper›PMID 37707890›Full record

ArticleOptics letters2023

Imaging human macular pigments with visible light optical coherence tomography and superluminescent diodes.

Alok K Gupta, Ruoyu Meng, Yasha S Modi, Vivek J Srinivasan

Open access · greenAbstract read
In one paragraph

Article in Optics letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Eye Dominance and Testing Order Effects in the Circularly-Oriented Macular Pigment Optical Density Measurements.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alok K Gupta
Ruoyu Meng
Yasha S Modi
Vivek J Srinivasan
NYU Langone Health · US

Funding

True Sub-Micron Ocular Diagnostics with Visible Light Optical Coherence TomographyR01EY031469 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SRINIVASAN, VIVEK JAY · 2020 to 2023
$2.3M
Human Brain Interferometers for Better Blood Flow MonitoringR01EB029747 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SRINIVASAN, VIVEK JAY · 2020 to 2023
$2.2M
Imaging Neuronal and Capillary Dysfunction Deep in the Rodent Brain in vivo Using 1700 NM Optical Coherence Microscopy and Tracer-Based KineticsR01NS094681 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SRINIVASAN, VIVEK JAY · 2015 to 2019
$1.6M
NEI NIH HHS R01 EY031469NIBIB NIH HHS R01 EB029747NINDS NIH HHS R01 NS094681
6 · The paper itself

Abstract

We demonstrate superluminescent diodes (SLDs) for visible light optical coherence tomography (OCT) of the human retina. SLDs are less costly than supercontinuum sources and have lower intrinsic excess noise, enabling imaging closer to the shot noise limit. While single SLDs are not broadband, they provide power concentrated at specific wavelengths relevant to retinal function. As a new, to the best of our knowledge, application, we image human macular pigments (MPs), which are thought to both aid vision and protect against advanced age-related macular degeneration. Using the unique depth-resolved capabilities of OCT, we localize MPs in depth to Henle's fibers beneath the foveal pit in the living human retina. Our approach reduces the cost of visible light OCT to nearly that of near-infrared (NIR) OCT while also providing information about clinically relevant MPs which cannot be measured in the NIR.

Indexed as

Macular PigmentTomography, Optical CoherenceHumansLightRetinaMacular Pigment

Identifiers

PMID37707890
PMCPMC10935566
OpenAlexW4385637225

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.