Evidence map›Paper›PMID 37707649›Full record

ArticleGeroScience2024

Associations between psychological resilience and epigenetic clocks in the health and retirement study.

Aijie Zhang, Yasi Zhang, Yaxian Meng, Qianqian Ji, Meijie Ye, Liqiong Zhou, Miao Liu, Chao Yi, Ida K Karlsson, Fang Fang and 2 more

Open access · greenAbstract read
In one paragraph

Article in GeroScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Premature aging in serious mental illness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Quantification of Epigenetic Aging in Public Health.Annual review of public health · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Aijie ZhangDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China.
Yasi ZhangDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China.
Yaxian MengDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China.
Qianqian JiDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China.
Meijie YeDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China.
Liqiong ZhouDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China. zhoulq28@mail.sysu.edu.cn.
Miao LiuDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China.
Chao YiDepartment of Chronic Disease Control, Guangming Center for Disease Control and Prevention, Shenzhen, China.
Ida K KarlssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Fang FangInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Sara HäggDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Yiqiang ZhanDepartment of Epidemiology, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen, China. zhanyq8@mail.sysu.edu.cn.ORCID 0000-0001-5815-9725
Sun Yat-sen University · CNKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the associations between psychological resilience and epigenetic clocks assessed by DNA methylation age predictions. We used data from 4018 participants in the Health and Retirement Study. Multivariable linear regression models were used to estimate the association between psychological resilience and epigenetic clocks adjusted for age, sex, race, body mass index, smoking status, and years of education. Thirteen epigenetic clocks were used in our analysis and were highly correlated with one another. A higher psychological resilience score was associated with slower DNA methylation age acceleration for the majority of epigenetic clocks after multivariable adjustment. These findings imply that people with a higher level of psychological resilience may experience slower DNA methylation age acceleration and biological aging.

Indexed as

Epigenesis, GeneticResilience, PsychologicalAgingDNA MethylationHumansRetirementAgingDNA methylationEpigenetic clockResilience

Identifiers

PMID37707649
PMCPMC10828333
OpenAlexW4386726771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.