Evidence map›Paper›PMID 37707495›Full record

ArticleeLife2023

A generic binding pocket for small molecule

Magnus Chan, Harutyun Sahakyan, Jodene Eldstrom, Daniel Sastre, Yundi Wang, Ying Dou, Marc Pourrier, Vitya Vardanyan, David Fedida

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Cannabidiol inhibits both human KActa pharmacologica Sinica · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Magnus Chan *Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
Harutyun Sahakyan *Laboratory of Computational Modeling of Biological Processes, Institute of Molecular Biology, Yerevan, Armenia.ORCID 0000-0003-3750-8118
Jodene Eldstrom *Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
Daniel SastreDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
Yundi WangDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
Ying DouDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
Marc PourrierDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.
Vitya VardanyanMolecular Neuroscience Group, Institute of Molecular Biology, Yerevan, Armenia.ORCID 0000-0001-6731-036X
David FedidaDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada.ORCID 0000-0001-6797-5185

Funding

CIHR PJT-175024
6 · The paper itself

Abstract

The cardiac

Indexed as

CalmodulinKCNQ1 Potassium ChannelAnimalsHeartHeart RateImmunologic FactorsMammalsCalmodulinImmunologic FactorsKCNQ1 Potassium Channelarrhythmiabiochemistrychemical biologyhearthumanpharmacologypotassium channel

Identifiers

PMID37707495
PMCPMC10501768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.