Trial reportJournal of the American Geriatrics Society2023
Technology caregiver intervention for Alzheimer's disease (I-CARE): Feasibility and preliminary efficacy of Brain CareNotes.
Trial report in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness of eHealth Interventions in Alleviating Burden on Informal Caregivers of People With Dementia: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- mHealth To Promote Monitoring and Self-Regulation Among Caregivers of People With Dementia: A Systematic Review.PsyCh journal · 2026Pooled it
- Digital technology-based dyadic interventions in patients with mild cognitive impairment or dementia and their caregivers: a scoping review.Frontiers in psychiatry · 2026Pooled it
- Effectiveness of Telephone Interventions for the Management of Behavioral and Psychological Symptoms of Dementia in the Community: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Development and effectiveness of a user-centered mobile application for informal caregivers of people living with dementia: randomized controlled trial.BMC geriatrics · 2026Trial
- Smartphone App-Based Psychoeducation for Caregivers of People with Dementia in Vietnam: A Pilot Randomized Controlled Trial.Clinical interventions in aging · 2025Trial
- The geographic digital divide among dementia caregivers in the U.S.: a cross-sectional study.BMC health services research · 2026Article
- The Feasibility and Preliminary Effects of a Stress Process Model-Based Program in Dementia Caregiving (DeCare-SPM) for Family Caregivers: A Mixed-Methods Pilot Study.Journal of multidisciplinary healthcare · 2026Article
- Mobile Telehealth Intervention to Support Care Partners of Patients With Alzheimer Disease and Related Dementias (I-CARE 2): Protocol for a Randomized Effectiveness Clinical Trial.JMIR research protocols · 2025Article
- Perspectives and Experiences of Family Caregivers Using Supportive Mobile Apps in Dementia Care: Meta-Synthesis of Qualitative Research.JMIR mHealth and uHealth · 2025Article
- Development, Implementation, and Outcomes of Web-Based Interventions for Family Caregivers of Individuals with Dementia: A Scoping Review.Risk management and healthcare policy · 2025Review
- Technology that CARES: Enhancing dementia care through everyday technologies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Interventions to Relieve the Burden on Informal Caregivers of Older People with Dementia: A Scoping Review.Nursing reports (Pavia, Italy) · 2024Article
- The effectiveness of virtual passport, an app-based intervention, for dementia care.Frontiers in psychiatry · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundThe primary aim of the current pilot study was to examine enrollment rate, data completion, usability, acceptance and use of a mobile telehealth application, Brain CareNotes. A secondary aim was to estimate the application's effect in reducing caregiver burden and behavioral and psychological symptoms related to dementia (BPSD).
methodsPatient-caregiver dyads (n = 53) were recruited and randomized to intervention and control groups. Assessment of usability, acceptance, BPSD symptoms, and caregiver burden were collected at baseline, 3- and 6-month follow-up.
resultsThe enrollment rate was acceptable despite pandemic related challenges (53/60 target recruitment sample). Among randomized individuals, there was a retention rate of 85% and data completion was attained for 81.5% of those allocated to usual care and 88.5% of those allocated to Brain CareNotes. Mean caregiver-reported app usability at 6 months was 72.5 (IQR 70.0-90.0) on the System Usability Scale-considered "Good to Excellent"-and user acceptance was reasonable as indicated by 85%-90% of caregivers reporting they would intend to use the app to some degree in the next 6 months, if able. Regarding intervention effect, although differences in outcome measures between the groups were not statistically significant, compared to baseline, we found a reduction of caregiver burden (NPI-Caregiver Distress) of 1.0 at 3 months and 0.7 at 6 months for those in the intervention group. BPSD (NPI Total Score) was also reduced from baseline by 4.0 at 3 months and by 0.5 at 6 months.
conclusionsBrain CareNotes is a highly scalable, usable and acceptable mobile caregiver intervention. Future studies should focus on testing Brain CareNotes on a larger sample size to examine efficacy of reducing caregiver burden and BPSD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.