Evidence map›Paper›PMID 37706509›Full record

ArticleLeukemia & lymphoma2023

Very low-dose radiotherapy for extranodal marginal zone lymphoma of bronchus-associated lymphoid tissue.

Morgan E Freret, Kathryn R Tringale, Lillian Boe, Brandon S Imber, Erel Joffe, Joachim Yahalom, Carla Hajj

Open access · hybridAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Article
  5. [Research Progress of Pulmonary Extranodal Marginal Zone Lymphoma].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Morgan E FreretRadiation Oncology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY, USA.ORCID 0000-0001-5189-716X
Kathryn R TringaleRadiation Oncology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY, USA.ORCID 0000-0002-1506-4870
Lillian BoeEpidemiology and Biostatistics, MSKCC, New York, NY, USA.ORCID 0000-0001-6279-9987
Brandon S ImberRadiation Oncology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY, USA.ORCID 0000-0002-1281-5915
Erel JoffeLymphoma Service, MSKCC, New York, NY, USA.ORCID 0000-0002-7883-289X
Joachim YahalomRadiation Oncology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY, USA.ORCID 0000-0003-1658-8585
Carla HajjRadiation Oncology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY, USA.ORCID 0000-0001-8774-1845
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Extranodal marginal zone lymphoma of bronchus-associated lymphoid tissue (BALT) is a rare cancer for which optimal treatment strategies are undefined. Retrospective analyses suggest excellent outcomes with surgical resection for localized BALT lymphoma; however, the role of radiotherapy remains underexplored. We report the largest-to-date single-center analysis of 13 primary BALT lymphoma patients treated with radiotherapy. Of 15 treated lesions, we report a 100% response rate with complete response (CR) achieved in 67% of lesions. Among 10 lesions treated with very low-dose radiotherapy (VLDRT; 4 Gray [Gy]), 6 (60%) achieved a CR; among 5 lesions treated with full-dose radiotherapy (24-36 Gy), 4 (80%) achieved a CR. There were no local recurrences. Only one patient, treated with 30 Gy, developed an acute grade 3/4 toxic effect. There were no events of radiation-induced secondary malignancies. Our institutional experience indicates that radiotherapy, including VLDRT, is a safe and effective treatment for primary BALT lymphoma.

Indexed as

Lymphoma, B-Cell, Marginal ZoneBronchiHumansLymphoid TissueRetrospective StudiesTreatment OutcomeBALT lymphomaExtranodal marginal zone lymphomapulmonary MALTradiationvery low-dose radiotherapy

Identifiers

PMID37706509
PMCPMC10962616
OpenAlexW4386726721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.