Evidence map›Paper›PMID 37706348›Full record

ArticleCancer medicine2023

Breast/ovarian cancer genetic counseling: Do anxiety, depression, and health care-related fears influence cancer worry and risk perception?

Anita Caruso, Gabriella Maggi, Cristina Vigna, Antonella Savarese, Laura Gallo, Lara Guariglia, Giulia Casu, Paola Gremigni

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anita CarusoPsychology Unit, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy.
Gabriella MaggiPsychology Unit, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy.
Cristina VignaPsychology Unit, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy.
Antonella SavareseDepartment of Oncology, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy.
Laura GalloPsychology Unit, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy.
Lara GuarigliaPsychology Unit, IRCCS "Regina Elena" National Cancer Institute, Rome, Italy.ORCID 0000-0001-7010-3716
Giulia CasuDepartment of Psychology, University of Bologna, Bologna, Italy.
Paola GremigniDepartment of Psychology, University of Bologna, Bologna, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of family and personal cancer history and emotional factors, such as depression and anxiety, on disease representation has received limited attention in studies investigating the development of cancer-related worry and risk perception within the context of genetic counseling. The current study endeavors to fill this gap by exploring the extent to which depression and anxiety influence cancer worry and risk perception, and the role of health care-related fear as potential mediator in this relationship.

methodsA sample of 178 women who underwent their first genetic counseling for breast/ovarian cancer, 52% of whom had previous cancer diagnoses, completed questionnaires assessing sociodemographic and clinical information, emotional distress in terms of anxiety and depression, cancer-related worry, risk perception, and health care-related fears.

resultsResults of mediation analyses showed that cancer-related worry and risk perception increased with rising levels of depression and anxiety, with health care-related fears acting as a mediator in the relationship of depression and anxiety with cancer worry and risk perception. Covariate analysis revealed that previous cancer diagnosis increases cancer-related worry but not risk perception, while the number of family members affected by cancer increases both outcomes.

conclusionThese findings emphasize the need for a holistic approach in genetic counseling and have implications for the clinical practice.

Indexed as

Breast NeoplasmsOvarian NeoplasmsAnxietyDelivery of Health CareDepressionFearFemaleGenetic CounselingGenetic Predisposition to DiseaseHumansPerceptionanxietyBRCA 1/2 genetic mutationcancercancer worrydepressionfamily historygenetic counselinghealth fearspsychological distressrisk perception

Identifiers

PMID37706348
PMCPMC10557864
OpenAlexW4386726187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.