Evidence map›Paper›PMID 37705893›Full record

ArticleApplied physics letters2023

Real-time spatiotemporal characterization of mechanics and sonoporation of acoustic droplet vaporization in acoustically responsive scaffolds.

Mitra Aliabouzar, Bachir A Abeid, Oliver D Kripfgans, J Brian Fowlkes, Jonathan B Estrada, Mario L Fabiilli

Open access · greenAbstract read
In one paragraph

Article in Applied physics letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bachir A AbeidDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.ORCID https://orcid.org/0009-0009-0859-8434
Jonathan B EstradaDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.ORCID https://orcid.org/0000-0003-1083-4597
University of Michigan · US

Funding

Angiogenic growth factor delivery for vascular regeneration in critical limb ischemia using acoustically-responsive scaffoldsR01HL139656 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mario Leonardo Fabiilli · 2018 to 2026
$5.7M
High-Speed Optical Imaging for Medical Diagnosis and TherapyS10RR022425 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRIPFGANS, OLIVER D · 2007 to 2007
$499k
NCRR NIH HHS S10 RR022425NHLBI NIH HHS R01 HL139656
6 · The paper itself

Abstract

Phase-shift droplets provide a flexible and dynamic platform for therapeutic and diagnostic applications of ultrasound. The spatiotemporal response of phase-shift droplets to focused ultrasound, via the mechanism termed acoustic droplet vaporization (ADV), can generate a range of bioeffects. Although ADV has been used widely in theranostic applications, ADV-induced bioeffects are understudied. Here, we integrated ultra-high-speed microscopy, confocal microscopy, and focused ultrasound for real-time visualization of ADV-induced mechanics and sonoporation in fibrin-based, tissue-mimicking hydrogels. Three monodispersed phase-shift droplets-containing perfluoropentane (PFP), perfluorohexane (PFH), or perfluorooctane (PFO)-with an average radius of ∼6

Identifiers

PMID37705893
PMCPMC10497320
OpenAlexW4386603920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.