ArticleLancet regional health. Americas2023
Respiratory syncytial virus epidemiology and clinical severity before and during the COVID-19 pandemic in British Columbia, Canada: a retrospective observational study.
Article in Lancet regional health. Americas, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Changes in Microbial Foodborne Pathogen Detection in Beijing, China, Before and After the COVID-19 Pandemic: Single-Center Retrospective Study.JMIR formative research · 2026Article
- Seasonal Patterns of Hospitalizations for Pediatric Acute Respiratory Diseases by Age Group and Sex in Alberta, Canada: A Population-Level Retrospective Cohort Study From 2010 to 2025.Open forum infectious diseases · 2026Article
- A comprehensive look at Respiratory Syncytial Virus (RSV): from pathogenesis to prevention.Tropical diseases, travel medicine and vaccines · 2026Review
- Respiratory syncytial virus infection in adults: Clinical manifestations, outcomes, and vaccines.Journal of the Chinese Medical Association : JCMA · 2026Review
- Epidemic dynamics and age-specific distribution of respiratory pathogens: a direct-to-consumer surveillance study in four regions of China, October 2023-February 2025.BMC infectious diseases · 2026Article
- Descriptive epidemiology of common respiratory pathogen infections in children: a retrospective cross-sectional study in Xinjiang, China.BMC infectious diseases · 2026Article
- Monitoring of RSV-A and RSV-B Circulation in Poland Across Three Post-Pandemic Seasons (2022-2025).Viruses · 2026Article
- Evaluating respiratory syncytial virus immunization strategies for infants in Canada: A cost-utility analysis.PloS one · 2026Article
- Normalization of Seasonality and Age Distribution of Pediatric RSV Infection Following the Pandemic Disruption in the Netherlands.Open forum infectious diseases · 2026Article
- Molecular Epidemiology of Pediatric Respiratory Infections in Xinjiang, China: A Cross-Sectional Study of Six Pathogens.Infection and drug resistance · 2026Article
- Interplay between climate and childhood mixing can explain a sudden shift in RSV seasonality in Japan.Nature communications · 2025Article
- Clinical and epidemiological characteristics of respiratory syncytial virus, SARS-CoV-2 and influenza paediatric viral respiratory infections in southwest Saudi Arabia.Annals of medicine · 2025Article
- Healthcare costs and resource utilization for acute respiratory syncytial virus pediatric hospitalizations in Canada: a population-based study.Lancet regional health. Americas · 2025Article
- Impact of RSV hospitalization on healthcare costs, caregivers' productivity loss, and quality of life in children ≤ 2 years old in five European countries.European journal of pediatrics · 2025Article
- Dynamics of RSV hospitalization rates in ≤ 2-year-old children between 2020-2023 in Europe.European journal of pediatrics · 2025Article
- Unraveling the role of viral interference in disrupting biennial RSV epidemics in northern Stockholm.Nature communications · 2025Article
- Pediatric COVID-19 severity by SARS-CoV-2 lineage and vaccine status in Canada: an IMPACT study.Pediatric research · 2025Article
- Pediatric Acute Respiratory Virus Hospitalizations: A Population-Based Cohort Study, 2017-2024.The Journal of infectious diseases · 2025Article
- Shifting epidemic trends and severity in pediatric Mycoplasma pneumoniae infections in the post-COVID-19 era.Italian journal of pediatrics · 2025Article
- Impact of the COVID-19 pandemic on the respiratory syncytial virus infections in children admitted with community acquired pneumonia: a retrospective study at a tertiary hospital of Northeast China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
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11 authors.
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Abstract
Background: The COVID-19 pandemic has perturbed the seasonality of respiratory syncytial virus (RSV) infections. However, we lack data on how this impacted the severity of paediatric RSV cases. The objective of this study was to describe the clinical severity of RSV cases before, during and after pandemic measures in British Columbia (BC), Canada. Methods: Retrospective study of RSV cases from September 1st, 2017 to May 15th, 2023, with a review of RSV outcomes in children below 18 years old at BC's paediatric hospital. Temporal changes in RSV cases and hospitalisations were quantified using interrupted time series. Findings: BC experienced only 11 RSV cases (from 95,266 tests) between September 2020 and August 2021. This was followed by a resurgence of 9,529 RSV cases (219,566 tests [4.3% positive tests]) in 2021-22 and 8,215 cases (124,449 tests [6.6% positive tests]) in 2022-23, increased compared to 1,750 cases (48,664 tests [3.6% positive tests]) per corresponding yearly period in 2017-20. From September 2017 to May 2023, the median age of children with RSV at BC Children's Hospital increased from 8.7 [IQR: 2.0-26.0] to 19.6 [3.9-43.7] months per yearly period. More children were hospitalised in 2022-23 (n = 360), compared to 2017-20 (n = 168 per period) and 2021-22 (n = 172). However, we detected no increase in hospitalisations or ICU admissions in children born prematurely or with chronic cardiorespiratory conditions. Interpretation: The increased detection of symptomatic RSV cases in older children in 2021-22 and increased RSV-related hospitalisations in 2022-23 suggest a gradual increase in the pool of immunologically vulnerable children due to a prolonged lack of viral exposure. Funding: Government of Canada via its COVID-19 Immunity Task Force.
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