Evidence map›Paper›PMID 37705500›Full record

ArticleMedical decision making : an international journal of the Society for Medical Decision Making

Assessing and Understanding Reactance, Self-Exemption, Disbelief, Source Derogation and Information Conflict in Reaction to Overdiagnosis in Mammography Screening: Scale Development and Preliminary Validation.

Laura D Scherer, Krithika Suresh, Carmen L Lewis, Kirsten J McCaffery, Jolyn Hersch, Joseph N Cappella, Brad Morse, Channing E Tate, Bridget S Mosley, Sarah Schmiege and 1 more

Abstract read
In one paragraph

Article in Medical decision making : an international journal of the Society for Medical Decision Making. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Skeptical reactions to breast cancer screening benefits and harms: Antecedents, consequences, and implications for screening communication.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laura D SchererDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-8660-7115
Krithika SureshDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Carmen L LewisAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado School of Medicine, Aurora, CO, USA.
Kirsten J McCafferyDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jolyn HerschDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Joseph N CappellaDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Brad MorseDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Channing E TateDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0001-6635-9794
Bridget S MosleyAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado School of Medicine, Aurora, CO, USA.
Sarah SchmiegeDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Marilyn M SchapiraDepartment of Medicine, University of Pennsylvania School of Medicine, Center for Health Equity Research & Promotion (CHERP), Philadelphia VA Medical Center, Philadelphia, PA, USA.ORCID 0000-0002-3775-9462

Funding

Understanding affective processing of scientific evidence to promote informed choice for breast cancer screeningR37CA254926 · NCI · UNIVERSITY OF COLORADO DENVER · PI Laura D. Scherer · 2021 to 2026
$3.8M
Understanding and addressing rejection of personalized cancer risk informationR01CA279953 · NCI · UNIVERSITY OF COLORADO DENVER · PI Laura D. Scherer, Erika A Waters · 2023 to 2026
$2.6M
NCI NIH HHS R01 CA279953NCI NIH HHS R37 CA254926
6 · The paper itself

Abstract

purposeOverdiagnosis is a concept central to making informed breast cancer screening decisions, and yet some people may react to overdiagnosis with doubt and skepticism. The present research assessed 4 related reactions to overdiagnosis: reactance, self-exemption, disbelief, and source derogation (REDS). The degree to which the concept of overdiagnosis conflicts with participants' prior beliefs and health messages (information conflict) was also assessed as a potential antecedent of REDS. We developed a scale to assess these reactions, evaluated how those reactions are related, and identified their potential implications for screening decision making.

methodsFemale participants aged 39 to 49 years read information about overdiagnosis in mammography screening and completed survey questions assessing their reactions to that information. We used a multidimensional theoretical framework to assess dimensionality and overall domain-specific internal consistency of the REDS and Information Conflict questions. Exploratory and confirmatory factor analyses were performed using data randomly split into a training set and test set. Correlations between REDS, screening intentions, and other outcomes were evaluated.

resultsFive-hundred twenty-five participants completed an online survey. Exploratory and confirmatory factor analyses identified that Reactance, Self Exemption, Disbelief, Source Derogation, and Information Conflict represent unique constructs. A reduced 20-item scale was created by selecting 4 items per construct, which showed good model fit. Reactance, Disbelief, and Source Derogation were associated with lower intent to use information about overdiagnosis in decision making and the belief that informing people about overdiagnosis is unimportant.

conclusionsREDS and Information Conflict are distinct but correlated constructs that are common reactions to overdiagnosis. Some of these reactions may have negative implications for making informed screening decisions. HIGHLIGHTS: Overdiagnosis is a concept central to making informed breast cancer screening decisions, and yet when provided information about overdiagnosis, some people are skeptical.This research developed a measure that assessed different ways in which people might express skepticism about overdiagnosis (reactance, self-exemption, disbelief, source derogation) and also the perception that overdiagnosis conflicts with prior knowledge and health messages (information conflict).These different reactions are distinct but correlated and are common reactions when people learn about overdiagnosis.Reactance, disbelief, and source derogation are associated with lower intent to use information about overdiagnosis in decision making as well as the belief that informing people about overdiagnosis is unimportant.

Indexed as

Breast NeoplasmsDecision MakingEarly Detection of CancerFemaleHumansMammographyMass ScreeningOverdiagnosisbreast cancer screeningdecision-makingdisbeliefoverdiagnosisskepticism

Identifiers

PMID37705500
PMCPMC10843591

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.