Evidence map›Paper›PMID 37705296›Full record

ArticleStatistics in medicine2023

Using temporal recalibration to improve the calibration of risk prediction models in competing risk settings when there are trends in survival over time.

Sarah Booth, Sarwar I Mozumder, Lucinda Archer, Joie Ensor, Richard D Riley, Paul C Lambert, Mark J Rutherford

Open access · hybridAbstract read
In one paragraph

Article in Statistics in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Sarah BoothBiostatistics Research Group, Department of Population Health Sciences, University of Leicester, Leicester, UK.ORCID 0000-0003-1799-3144
Sarwar I MozumderBiostatistics Research Group, Department of Population Health Sciences, University of Leicester, Leicester, UK.ORCID 0000-0001-9644-7525
Lucinda ArcherInstitute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0003-2504-2613
Joie EnsorInstitute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0001-7481-0282
Richard D RileyInstitute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0001-8699-0735
Paul C LambertBiostatistics Research Group, Department of Population Health Sciences, University of Leicester, Leicester, UK.ORCID 0000-0002-5337-663X
Mark J RutherfordBiostatistics Research Group, Department of Population Health Sciences, University of Leicester, Leicester, UK.ORCID 0000-0003-1557-6697
University of Birmingham · GBUniversity of Leicester · GBAstraZeneca (United Kingdom) · GB

Funding

Cancer Research UK 27583Cancer Research UK C14183/A29739Cancer Research UK C41379/A27583
6 · The paper itself

Abstract

We have previously proposed temporal recalibration to account for trends in survival over time to improve the calibration of predictions from prognostic models for new patients. This involves first estimating the predictor effects using data from all individuals (full dataset) and then re-estimating the baseline using a subset of the most recent data whilst constraining the predictor effects to remain the same. In this article, we demonstrate how temporal recalibration can be applied in competing risk settings by recalibrating each cause-specific (or subdistribution) hazard model separately. We illustrate this using an example of colon cancer survival with data from the Surveillance Epidemiology and End Results (SEER) program. Data from patients diagnosed in 1995-2004 were used to fit two models for deaths due to colon cancer and other causes respectively. We discuss considerations that need to be made in order to apply temporal recalibration such as the choice of data used in the recalibration step. We also demonstrate how to assess the calibration of these models in new data for patients diagnosed subsequently in 2005. Comparison was made to a standard analysis (when improvements over time are not taken into account) and a period analysis which is similar to temporal recalibration but differs in the data used to estimate the predictor effects. The 10-year calibration plots demonstrated that using the standard approach over-estimated the risk of death due to colon cancer and the total risk of death and that calibration was improved using temporal recalibration or period analysis.

Indexed as

Colonic NeoplasmsCalibrationHumansPrognosisProportional Hazards Modelscalibrationcompeting risksprognostic modelsrisk predictiontemporal recalibration

Identifiers

PMID37705296
PMCPMC10946485
OpenAlexW4386725718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.