Evidence map›Paper›PMID 37705004›Full record

ReviewMalaria journal2023

The impact of anti-malarial markets on artemisinin resistance: perspectives from Burkina Faso.

Rosemonde M Guissou, Chanaki Amaratunga, Freek de Haan, Fatoumata Tou, Phaik Yeong Cheah, R Serge Yerbanga, Ellen H M Moors, Mehul Dhorda, Paulina Tindana, Wouter P C Boon and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Rosemonde M GuissouInstitut de Recherche en Sciences de la Sante, Centre National de la Recherche Scientifique et Technologique, Ouagadougou, Burkina Faso. rosyguiss@yahoo.fr.
Chanaki AmaratungaMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Freek de HaanCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Fatoumata TouInstitut des Sciences et Techniques, Bobo-Dioulasso, Burkina Faso.
Phaik Yeong CheahMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
R Serge YerbangaInstitut de Recherche en Sciences de la Sante, Centre National de la Recherche Scientifique et Technologique, Ouagadougou, Burkina Faso.
Ellen H M MoorsCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Mehul DhordaMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Paulina TindanaSchool of Public Health, College of Health Sciences, University of Ghana, Accra, Ghana.
Wouter P C BoonCopernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands.
Arjen M DondorpMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Jean Bosco OuédraogoInstitut des Sciences et Techniques, Bobo-Dioulasso, Burkina Faso.
Utrecht University · NLCentre National de la Recherche Scientifique et Technologique · BFInstitut de Recherche en Sciences de la Santé · BFMahidol University · THUniversity of Oxford · GBUniversity of Ghana · GH

Funding

Wellcome TrustWellcome Trust 220211
6 · The paper itself

Abstract

backgroundWidespread artemisinin resistance in Africa could be catastrophic when drawing parallels with the failure of chloroquine in the 1970s and 1980s. This article explores the role of anti-malarial market characteristics in the emergence and spread of arteminisin resistance in African countries, drawing on perspectives from Burkina Faso.

methodsData were collected through in-depth interviews and focus group discussions. A representative sample of national policy makers, regulators, public and private sector wholesalers, retailers, clinicians, nurses, and community members were purposively sampled. Additional information was also sought via review of policy publications and grey literature on anti-malarial policies and deployment practices in Burkina Faso.

resultsThirty seven in-depth interviews and 6 focus group discussions were conducted. The study reveals that the current operational mode of anti-malarial drug markets in Burkina Faso promotes arteminisin resistance emergence and spread. The factors are mainly related to the artemisinin-based combination therapy (ACT) supply chain, to ACT quality, ACT prescription monitoring and to ACT access and misuse by patients.

conclusionStudy findings highlight the urgent requirement to reform current characteristics of the anti-malarial drug market in order to delay the emergence and spread of artemisinin resistance in Burkina Faso. Four recommendations for public policy emerged during data analysis: (1) Address the suboptimal prescription of anti-malarial drugs, (2) Apply laws that prohibit the sale of anti-malarials without prescription, (3) Restrict the availability of street drugs, (4) Sensitize the population on the value of compliance regarding correct acquisition and intake of anti-malarials. Funding systems for anti-malarial drugs in terms of availability and accessibility must also be stabilized.

Indexed as

AntimalarialsArtemisininsAdministrative PersonnelBurkina FasoChloroquineHumansAntimalarialsArtemisininsChloroquineACTAntimalarial marketArtemisinin resistanceBurkina FasoMalaria

Identifiers

PMID37705004
PMCPMC10498571
OpenAlexW4386712237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.