Evidence map›Paper›PMID 37704988›Full record

ArticleBMC biology2023

The dynamics of deltamethrin resistance evolution in Aedes albopictus has an impact on fitness and dengue virus type-2 vectorial capacity.

Yijia Guo, Ke Hu, Jingni Zhou, Zhensheng Xie, Yijie Zhao, Siyu Zhao, Jinbao Gu, Xiaohong Zhou, Guiyun Yan, Anthony A James and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yijia GuoDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
Ke HuDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
Jingni ZhouDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
Zhensheng Xie
Yijie ZhaoDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
Siyu ZhaoDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
Jinbao GuDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
Xiaohong ZhouDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China.
Guiyun YanProgram in Public Health, University of California, Irvine, Irvine, CA, USA.
Anthony A JamesDepartment of Microbiology & Molecular Genetics, University of California, Irvine, CA, 92697-4025, USA. aajames@uci.edu.ORCID http://orcid.org/0000-0001-5577-3308
Xiao-Guang ChenDepartment of Pathogen Biology, Institute of Tropical Medicine, School of Public Health, Southern Medical University, Guangzhou, China. xgchen@smu.edu.cn.ORCID http://orcid.org/0000-0002-7927-691X
Southern Medical University · CNUniversity of California, Irvine · US

Funding

Impacts of Urbanization on Vector Biology and Transmission of Dengue in ChinaR01AI136850 · NIAID · SOUTHERN MEDICAL UNIVERSITY · PI CHEN, XIAOGUANG · 2018 to 2022
$667k
NIAID NIH HHS R01 AI136850
6 · The paper itself

Abstract

backgroundWorldwide invasion and expansion of Aedes albopictus, an important vector of dengue, chikungunya, and Zika viruses, has become a serious concern in global public health. Chemical insecticides are the primary means currently available to control the mosquito populations. However, long-term and large-scale use of insecticides has selected for resistance in the mosquito that is accompanied by a genetic load that impacts fitness.

resultsA number of laboratory strains representing different resistance mechanisms were isolated and identified from laboratory-derived, deltamethrin-resistant Ae. albopictus recovered in previous work. Resistance levels and fitness costs of the strains were evaluated and compared to characterize the evolution of the resistance genotypes and phenotypes. The heterozygous F1534S mutation (1534

conclusionsThis study reveals a possible mechanism for the evolution of deltamethrin resistance in Aedes albopictus. These findings will help guide practical strategies for insecticide use, resistance management and the prevention and control of mosquito-borne disease.

Indexed as

AedesDengue VirusInsecticidesZika VirusZika Virus InfectionAnimalsMosquito VectorsNitrilesPyrethrinsdecamethrinInsecticidesNitrilesPyrethrinsMetabolic resistancePyrethroidSelectionTarget-site resistanceVector competence

Identifiers

PMID37704988
PMCPMC10500878
OpenAlexW4386710363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.