Evidence map›Paper›PMID 37704928›Full record

ArticleMolecular neurobiology2024

SNX17 Mediates Dendritic Spine Maturation via p140Cap.

Qiuyan Cui, Shiqi Liang, Hao Li, Yiqing Guo, Junkai Lv, Xinyuan Wang, Pengwei Qin, Huaxi Xu, Timothy Y Huang, Youming Lu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Qiuyan Cui *The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China.
Shiqi Liang *The Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China.
Hao LiThe Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China.
Yiqing GuoThe Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China.
Junkai LvThe Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China.
Xinyuan WangDepartment of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Chongqing, 400016, China.
Pengwei QinThe Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China.
Huaxi XuInstitute for Brain Science and Disease, Chongqing Medical University, Chongqing, 400016, China.
Timothy Y HuangDegenerative Diseases Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA.
Youming LuThe Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China.
Qing TianThe Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China. tianq@hust.edu.cn.
Tongmei ZhangThe Institute for Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, 430030, China. zhtm@hust.edu.cn.ORCID http://orcid.org/0000-0002-5973-5795
Huazhong University of Science and Technology · CNChongqing Medical University · CNSanford Burnham Prebys Medical Discovery Institute · USTongji Hospital · CN

Funding

National Natural Science Foundation of China 31721002National Natural Science Foundation of China 31930051National Natural Science Foundation of China 32200795National Natural Science Foundation of China 8180113National Natural Science Foundation of China 81920208014Natural Science Foundation of Hubei Province 2022CFB608
6 · The paper itself

Abstract

Sorting nexin17 (SNX17) is a member of the sorting nexin family, which plays a crucial role in endosomal trafficking. Previous research has shown that SNX17 is involved in the recycling or degradation of various proteins associated with neurodevelopmental and neurological diseases in cell models. However, the significance of SNX17 in neurological function in the mouse brain has not been thoroughly investigated. In this study, we generated Snx17 knockout mice and observed that the homozygous deletion of Snx17 (Snx17

Indexed as

Dendritic SpinesSorting NexinsAnimalsCarrier ProteinsHomozygoteMiceProtein TransportSequence DeletionCarrier Proteinsp140cap protein, mouseSnx17 protein, mouseSorting NexinsAnxiety-like behaviorsDendritic spine maturationp140CapSNX17

Identifiers

PMID37704928
OpenAlexW4386718961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.