Evidence map›Paper›PMID 37704908›Full record

ArticleJournal of thrombosis and thrombolysis2024

Prevalence of atrial fibrillation and reasons for undertreatment with oral anticoagulants.

Johan Lilja, Anders Själander, Sara Själander

Registry-linked trialAbstract read
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07705282 (Standalone Thoracoscopic Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07705282 nanot yet recruitingnot on this mapstarted 2028, after this paper: background citation

Standalone Thoracoscopic Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation

TypeinterventionalSponsorRegion SkaneRan2028 to 2032Enrolled936ConditionsATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION, Oral Anticoagulation, ThoracotomyArmsVideo-assisted thoracoscopic closure of the left atrial appendage using a closure device and discontinuation of treatment if the patient is treated with OAC
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Anticoagulation Optimization Through a Specialized Center for Atrial Fibrillation.American journal of medical quality : the official journal of the American College of Medical Quality
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Johan LiljaDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Anders SjälanderDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Sara SjälanderDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden. sara.sjalander@rvn.se.ORCID http://orcid.org/0000-0002-1239-6239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the prevalence of atrial fibrillation (AF), the proportion of AF patients not receiving oral anticoagulation (OAC) and reasons for abstaining from OAC treatment.

methodsA retrospective cross-sectional study of patients aged 18 years or older with an AF diagnosis on June 1st 2020 in Västernorrland County, Sweden. AF diagnosis was retrieved using the ICD10 code I.48, and medical records were reviewed for comorbidities and documented reasons to abstain OAC treatment.

resultsOf 197 274 residents in Västernorrland County, 4.7% (9 304/197 274) had a documented AF diagnosis. Of these, 19% (1 768/9 304) had no OAC treatment, including 4.2% (393/9 304) with no indication, 2.5% (233/9 304) with a questionable and 2.5% (231/9 304) with a documented clear contraindication for OAC. In total 9.8% (911/9 304) were not treated with OAC despite indication and no reasonable documented contraindication, thus 90.8% (8 447/9 304) of all AF-patients were eligible for OAC treatment. Common reasons for abstaining treatment without reasonable contraindication were present sinus rhythm in 13.7% (125/911), perceived not an OAC candidate in 10.6% (97/911) and anemia in the past in 4.3% (39/911).

conclusionsIn the population of Västernorrland County, a very high AF prevalence of 4.7% was found, of which just over 90% would theoretically benefit from OAC treatment. This is higher than previously reported and stresses the importance of stroke prevention in this large patient group.

Indexed as

Atrial FibrillationStrokeAdministration, OralAnticoagulantsCross-Sectional StudiesHumansPrevalenceRetrospective StudiesRisk FactorsUndertreatmentAnticoagulantsAtrial fibrillationOral anticoagulationPrevalence

Identifiers

PMID37704908
PMCPMC10830806

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.