Evidence map›Paper›PMID 37704863›Full record

ArticleCardiovascular and interventional radiology2023

Hepatic Arteriography and C-Arm CT-Guided Ablation (HepACAGA) to Improve Tumor Visualization, Navigation and Margin Confirmation in Percutaneous Liver Tumor Ablation.

Maarten L J Smits, Rutger C G Bruijnen, Philip Tetteroo, Evert-Jan P A Vonken, Martijn R Meijerink, Jeroen Hagendoorn, Joep de Bruijne, Warner Prevoo

Open access · hybridAbstract read
In one paragraph

Article in Cardiovascular and interventional radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Maarten L J SmitsDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands. m.l.j.smits-3@umcutrecht.nl.ORCID http://orcid.org/0000-0003-4735-655X
Rutger C G BruijnenDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Philip TetterooDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Evert-Jan P A VonkenDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Martijn R MeijerinkDepartment of Radiology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Jeroen HagendoornDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Joep de BruijneDepartment of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands.
Warner PrevooDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
University Medical Center Utrecht · NLAmsterdam University Medical Centers · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe present a technique that combines Hepatic Arteriography with C-arm CT-Guided Ablation (HepACAGA) to improve tumor visualization, navigation and margin confirmation for percutaneous ablation of liver tumors. MATERIALS AND

methodsAll consecutive patients scheduled for HepACAGA between April 20th, 2021, and November 2nd, 2021, were included in this retrospective, cohort study. HepACAGA was performed in an angiography-suite under general anesthesia. The hepatic artery was catheterized for selective contrast injection. C-arm CT and guidance software were then used to visualize the tumor and the microwave antenna was inserted during apnea. Pre- and post-ablation C-arm CTs were performed and ablation margins assessed. Technical success, antenna placement deviation, number of repositions, tumor recurrence, and safety were evaluated. Technical success was defined as a tumor that was ablated according to the HepACAGA technique.

resultsA total of 21 patients (28 tumors) were included. The main tumor type was colorectal cancer liver metastases (11/21, 52%), followed by hepatocellular carcinoma (7/21, 33%), neuroendocrine tumor metastases (1/21, 5%), and other tumor types (2/21, 10%). The technical success rate was 93% (26/28 tumors) with two small hypovascular lesions unable to be identified. A single microwave antenna was used in all patients. The median antenna placement deviation was 1 mm (range 0-6 mm). At a median follow-up time of 16 months (range 5-22 months), there was no tumor recurrence in any patient. Safety analysis showed a complication rate of 5% grade 2 and 5% grade 3.

conclusionHepACAGA was demonstrated to be a safe and effective percutaneous ablation technique, without any local tumor recurrence in this study.

Indexed as

Catheter AblationComputed Tomography AngiographyHepatic ArteryLiver NeoplasmsRadiography, InterventionalSurgery, Computer-AssistedAdultAgedAged, 80 and overCarcinoma, HepatocellularFemaleHumansMaleMargins of ExcisionMicrowavesMiddle AgedAblationCatheterColorectal cancerCone beam CTCTHAHepatocellular carcinomaLiverMicrowave

Identifiers

PMID37704863
PMCPMC10547639
OpenAlexW4386709015

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.