Evidence map›Paper›PMID 37704730›Full record

ArticleNature2023

Clustering predicted structures at the scale of the known protein universe.

Inigo Barrio-Hernandez, Jingi Yeo, Jürgen Jänes, Milot Mirdita, Cameron L M Gilchrist, Tanita Wein, Mihaly Varadi, Sameer Velankar, Pedro Beltrao, Martin Steinegger

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 195 papers.

0numbers the graph read from it
0cells of the map it votes in
195citing papers in PubMed
51.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

195 citing papers in PubMed, 337 citations in OpenAlex.

  1. Article
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  3. A structure-aware generative AI framework for revealing functional relationships in protein families.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  7. Robots and Minimal, Physics-Informed Features: A Hybrid Framework for Enzyme Catalysis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Systematic discovery of circular permutations across the protein universe using CIRPIN.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  18. A Noncontiguous Code for RNA-Guided DNA Recognition Preceded CRISPR.bioRxiv : the preprint server for biology · 2026
    Article
  19. Article
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135 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 6 countries.

Inigo Barrio-Hernandez *European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-5686-0451
Jingi Yeo *School of Biological Sciences, Seoul National University, Seoul, South Korea.
Jürgen JänesDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Milot MirditaSchool of Biological Sciences, Seoul National University, Seoul, South Korea.ORCID 0000-0001-8637-6719
Cameron L M GilchristSchool of Biological Sciences, Seoul National University, Seoul, South Korea.
Tanita WeinDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Mihaly VaradiEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK.
Sameer VelankarEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK.ORCID 0000-0002-8439-5964
Pedro BeltraoDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland. beltrao@imsb.biol.ethz.ch.ORCID 0000-0002-2724-7703
Martin SteineggerSchool of Biological Sciences, Seoul National University, Seoul, South Korea. martin.steinegger@snu.ac.kr.ORCID 0000-0001-8781-9753
Seoul National University · KREuropean Bioinformatics Institute · GBETH Zurich · CHSIB Swiss Institute of Bioinformatics · CHWeizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins are key to all cellular processes and their structure is important in understanding their function and evolution. Sequence-based predictions of protein structures have increased in accuracy

Indexed as

AlgorithmsCluster AnalysisProteinsStructural Homology, ProteinDatabases, ProteinEvolution, MolecularHumansMolecular Sequence AnnotationPhylogenyProkaryotic CellsSequence AlignmentSpecies SpecificityProteins

Identifiers

PMID37704730
PMCPMC10584675
OpenAlexW4386708656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.